Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | OXER1 | Q8TDS5 | 5/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | PPARG | P37231 | 3/20 | 0.38 |
| ▸ | RXRA | P19793 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 3/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.36 |
| ▸ | F7 | P08709 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3265006 | 1.00 | ADORA3 (0.46) | ADORA3NR1I2PTGS2PGRPDE4D | |
| SCHEMBL3265008 | 1.00 | ADORA3 (0.46) | ADORA3NR1I2PTGS2PGRPDE4D | |
| SCHEMBL13491252 | 0.95 | ADORA3 (0.50) | ADORA3NR1I2PTGS2PGRPDE4D | |
| SCHEMBL441945 | 0.86 | PTGS2 (0.46) | ADORA3NR1I2PTGS2PGRPDE4D | |
| SCHEMBL3226490 | 0.86 | PTGS2 (0.46) | ADORA3NR1I2PTGS2PGRPDE4D | |
| SCHEMBL3226480 | 0.86 | PTGS2 (0.46) | ADORA3NR1I2PTGS2PGRPDE4D | |
| SCHEMBL2879036 | 0.83 | ADORA3 (0.51) | ADORA3NR1I2PTGS2PGRPDE4D | |
| SCHEMBL4456986 | 0.82 | ALDH1A1 (0.44) | ADORA3NR1I2PTGS2PGRPDE4D | |
| SCHEMBL13491259 | 0.82 | ADORA3 (0.50) | ADORA3NR1I2PTGS2PGRPDE4D | |
| SCHEMBL3216696 | 0.82 | ADORA3 (0.43) | ADORA3NR1I2PTGS2PGRPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888727-B1 | NEW DHA DERIVATIVES AND THEIR USE AS MEDICAMENTS | PRONOVA BIOPHARMA NORGE AS (NO) | 2015-04-15 | — | — | EP | disclosed |
| US-20120065260-A1 | NOVEL COMPOUNDS | Pronova BioPhrma Norge AS | 2012-03-15 | — | — | US | disclosed |
| US-20120065260-A1 | NOVEL COMPOUNDS | Pronova BioPhrma Norge AS | 2012-03-15 | — | — | US | disclosed |
| US-8034842-B2 | Compounds | PRONOVA BIOPHARMA NORGE AS (NO) | 2011-10-11 | — | — | US | disclosed |
| US-8034842-B2 | Compounds | PRONOVA BIOPHARMA NORGE AS (NO) | 2011-10-11 | — | — | US | disclosed |
| US-20110166228-A1 | COMPOSITION | PRONOVA BIOPHARMA NORGE AS (NO) | 2011-07-07 | — | — | US | disclosed |
| US-7550613-B2 | alpha-methoxy docosahexanoic acid ethyl ester, alpha-iodo-docosahexanoic acid ethyl ester; antidiabetic for diabetes type 2, cardiovascular disorders, obesity, amyloidosis, prophylaxis; free of 4,7,10,13,16,19-docosahexanoic acid ( DHA), alpha-methyl DHA, alpha-methyl DHA-methyl ester | PRONOVA BIOPHARMA NORGE AS (NO) | 2009-06-23 | — | — | US | disclosed |
| US-7550613-B2 | alpha-methoxy docosahexanoic acid ethyl ester, alpha-iodo-docosahexanoic acid ethyl ester; antidiabetic for diabetes type 2, cardiovascular disorders, obesity, amyloidosis, prophylaxis; free of 4,7,10,13,16,19-docosahexanoic acid ( DHA), alpha-methyl DHA, alpha-methyl DHA-methyl ester | PRONOVA BIOPHARMA NORGE AS (NO) | 2009-06-23 | — | — | US | disclosed |
| US-20080300306-A1 | Novel Compounds | BRYHN MORTEN | 2008-12-04 | — | — | US | disclosed |
| US-20080300306-A1 | Novel Compounds | BRYHN MORTEN | 2008-12-04 | — | — | US | disclosed |
| US-20070088170-A1 | Novel compounds | PRONOVA BIOPHARMA NORGE AS (NO) | 2007-04-19 | — | — | US | disclosed |
| US-20070088170-A1 | Novel compounds | PRONOVA BIOPHARMA NORGE AS (NO) | 2007-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110166228-A1 | COMPOSITION | ELOVL3, FFAR3, ALOX5 | ADORA3 209/4885NR1I2 597/4885PTGS2 640/4885 |
| US-20070088170-A1 | Novel compounds | FFAR2, GPR119, ALOX12 | ADORA3 756/4885NR1I2 273/4885PTGS2 334/4885 |
| US-20080300306-A1 | Novel Compounds | GPR119, FFAR2, ALOX12 | ADORA3 730/4885NR1I2 288/4885PTGS2 371/4885 |
| US-20120065260-A1 | NOVEL COMPOUNDS | FFAR2, GPR119, ALOX12 | ADORA3 756/4885NR1I2 273/4885PTGS2 334/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.