Sugi Predict

Sugi Predict / Compounds / SCHEMBL4445451

SCHEMBL4445451

SCHEMBL4445451

CCc1ccc(-c2nccc3ccccc23)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 3/20 0.47
▸ NPC1 O15118 3/20 0.47
▸ RAB9A P51151 3/20 0.47
▸ MAPT P10636 2/20 0.47
▸ SMN1; SMN2 Q16637 2/20 0.47
▸ CYP1A2 P05177 2/20 0.47
▸ ALDH1A1 P00352 1/20 0.47
▸ CYP3A4 P08684 1/20 0.47
▸ HPGD P15428 1/20 0.47
▸ MAPK1 P28482 1/20 0.47
▸ CASP1 P29466 1/20 0.47
▸ CYP2C19 P33261 1/20 0.47
▸ CASP7 P55210 1/20 0.47
▸ ATM Q13315 1/20 0.47
▸ HSD17B10 Q99714 1/20 0.47
▸ L3MBTL1 Q9Y468 2/20 0.47
▸ GPR55 Q9Y2T6 1/20 0.47
▸ GLA P06280 1/20 0.46
▸ KMT2A Q03164 1/20 0.46
▸ NPSR1 Q6W5P4 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3142406 0.87 PDE10A (0.48) KDM4ENPC1RAB9AMAPTSMN1; SMN2
SCHEMBL12112873 0.86 MAPT (0.58) KDM4ENPC1RAB9AMAPTSMN1; SMN2
SCHEMBL10460557 0.84 HSD11B1 (0.46) KDM4ENPC1RAB9AMAPTSMN1; SMN2
SCHEMBL12970134 0.83 KDM4E (0.47) KDM4ENPC1RAB9AMAPTSMN1; SMN2
SCHEMBL28242249 0.83 ADRB2 (0.49) KDM4ENPC1RAB9AMAPTSMN1; SMN2
SCHEMBL27551421 0.83 HSD11B1 (0.47) KDM4ENPC1RAB9AMAPTSMN1; SMN2
SCHEMBL20258687 0.83 KDM4E (0.44) KDM4ENPC1RAB9AMAPTSMN1; SMN2
SCHEMBL28746601 0.82 HSD17B10 (0.46) KDM4ENPC1RAB9AMAPTSMN1; SMN2
SCHEMBL3134468 0.82 HSD17B10 (0.46) KDM4ENPC1RAB9AMAPTSMN1; SMN2
SCHEMBL3142147 0.82 HSD17B10 (0.46) KDM4ENPC1RAB9AMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11495755-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-11-08 — — US disclosed
EP-3719099-B1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORP (US) 2022-09-14 — — EP disclosed
EP-3719099-A1 PHOSPHORESCENT MATERIALS Universal Display Corporation (US) 2020-10-07 — — EP disclosed
US-20200176693-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-06-04 — — US disclosed
US-20200176693-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-06-04 — — US disclosed
EP-3327100-B1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORP (US) 2020-05-06 — — EP disclosed
US-10600975-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-03-24 — — US disclosed
US-10600975-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-03-24 — — US disclosed
US-20190157576-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-05-23 — — US disclosed
US-20190157576-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-05-23 — — US disclosed
CN-101657518-A phosphorescent material UNIV DISPLAY CORP US 2010-02-24 — — CN disclosed
EP-2121871-A2 PHOSPHORESCENT MATERIALS University Display Corporation (US) 2009-11-25 — — EP disclosed
US-20080261076-A1 Substituted 2-Phenyl quinoline complex with Iridium; high device efficiency, stability, and processibility UNIVERSAL DISPLAY CORPORATION (US) 2008-10-23 — — US disclosed
US-20080261076-A1 Substituted 2-Phenyl quinoline complex with Iridium; high device efficiency, stability, and processibility UNIVERSAL DISPLAY CORPORATION (US) 2008-10-23 — — US disclosed
US-20080261076-A1 Substituted 2-Phenyl quinoline complex with Iridium; high device efficiency, stability, and processibility UNIVERSAL DISPLAY CORPORATION (US) 2008-10-23 — — US disclosed
WO-2008109824-A2 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2008-09-12 — — WO disclosed
WO-2008109824-A2 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2008-09-12 — — WO disclosed
CN-100375749-C Luminescence device and display apparatus CANON KK (JP) 2008-03-19 — — CN disclosed
CN-1285601-C Light emitting device and display CANON KK (JP) 2006-11-22 — — CN disclosed
CN-1781925-A Luminescence device and display apparatus CANON KK (JP) 2006-06-07 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080261076-A1 Substituted 2-Phenyl quinoline complex with Iridium; high device efficiency, stability, and processibility PCID2, ICMT, ORAI2 KDM4E 2381/4885NPC1 3616/4885RAB9A 1685/4885
US-20200176693-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES RUVBL2, TERT, OR10J3 KDM4E 3403/4885NPC1 4327/4885RAB9A 1698/4885
US-11495755-B2 Organic electroluminescent materials and devices RUVBL2, TERT, OR10J3 KDM4E 3403/4885NPC1 4327/4885RAB9A 1698/4885
US-10600975-B2 Organic electroluminescent materials and devices TERT, OR10J3, RUVBL2 KDM4E 3344/4885NPC1 4327/4885RAB9A 1716/4885
US-20190157576-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES PIEZO1, ORAI2, PORCN KDM4E 3726/4885NPC1 3813/4885RAB9A 2720/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.