SCHEMBL446878

SCHEMBL446878

CCCCCCCC/C=C\CCCCCCCCOC[C@H](COP(=O)(O)OCCN)OCCCCCCCC/C=C\CCCCCCCC

nearest known ligand 0.65

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ PLA2G2C Q5R387 1/20 0.65
▸ LPAR1 Q92633 6/20 0.61
▸ LPAR3 Q9UBY5 6/20 0.61
▸ P2RY10 O00398 5/20 0.59
▸ LPAR2 Q9HBW0 1/20 0.54
▸ PLA2G2D Q9UNK4 1/20 0.48
▸ GPR34 Q9UPC5 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20582480 1.00 PLA2G2C (0.65) PLA2G2CLPAR1LPAR3P2RY10LPAR2
SCHEMBL666363 1.00 PLA2G2C (0.65) PLA2G2CLPAR1LPAR3P2RY10LPAR2
SCHEMBL22556278 1.00 PLA2G2C (0.65) PLA2G2CLPAR1LPAR3P2RY10LPAR2
SCHEMBL19878648 1.00 PLA2G2C (0.65) PLA2G2CLPAR1LPAR3P2RY10LPAR2
SCHEMBL6829952 1.00 PLA2G2C (0.65) PLA2G2CLPAR1LPAR3P2RY10LPAR2
SCHEMBL28722720 1.00 PLA2G2C (0.65) PLA2G2CLPAR1LPAR3P2RY10LPAR2
SCHEMBL31096006 0.97 PLA2G2C (0.61) PLA2G2CLPAR1LPAR3P2RY10LPAR2
SCHEMBL28927332 0.95 PLA2G2C (0.59) PLA2G2CLPAR1LPAR3P2RY10LPAR2
SCHEMBL28927329 0.95 PLA2G2C (0.59) PLA2G2CLPAR1LPAR3P2RY10LPAR2
SCHEMBL25394384 0.93 PLA2G2C (0.73) PLA2G2CLPAR1LPAR3P2RY10LPAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 929 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12636252-B2 Process of preparing mRNA-loaded lipid nano particles TRANSLATE BIO, INC. (US) 2026-05-26 — — US claimed
US-20260115221-A1 SYNERGISTIC ENHANCEMENT OF THE DELIVERY OF NUCLEIC ACIDS VIA BLENDED FORMULATIONS TRANSLATE BIO INC (US) 2026-04-30 — — US claimed
EP-4712948-A2 GENE EDITING SYSTEMS AND COMPOSITIONS FOR TREATMENT OF HEMOGLOBINOPATHIES AND METHODS OF USING THE SAME Renagade Therapeutics Management Inc. (US) 2026-03-25 — — EP claimed
US-12569572-B2 Messenger RNA therapy for the treatment of Friedreich's ataxia TRANSLATE BIO, INC. (US) 2026-03-10 — — US claimed
EP-4637813-A1 RHINOVIRUS MRNA VACCINE Sanofi Pasteur (FR) 2025-10-29 — — EP claimed
US-12453739-B2 Synergistic enhancement of the delivery of nucleic acids via blended formulations TRANSLATE BIO, INC. (US) 2025-10-28 — — US claimed
EP-4633673-A1 MRNA ENCODING INFLUENZA VIRUS-LIKE PARTICLE Sanofi Pasteur Inc. (US) 2025-10-22 — — EP claimed
EP-4619378-A2 IONIZABLE LIPIDS AND LIPID NANOPARTICLE COMPOSITIONS FOR THE DELIVERY OF NUCLEIC ACIDS Seawolf Therapeutics, Inc. (US) 2025-09-24 — — EP claimed
EP-4614148-A2 SYNERGISTIC ENHANCEMENT OF THE DELIVERY OF NUCLEIC ACIDS VIA BLENDED FORMULATIONS Translate Bio, Inc. (US) 2025-09-10 — — EP claimed
US-20250268994-A1 Optimized Nucleotide Sequences Encoding the Extracellular Domain of Human ACE2 Protein or a Portion Thereof TRANSLATE BIO, INC. (US) 2025-08-28 — — US claimed
US-20120065138-A1 LIPIDS, LIPID COMPLEXES AND USE THEREOF SILENCE THERAPEUTICS AG (DE) 2012-03-15 — — US claimed
US-20100062967-A1 COATED LIPID COMPLEXES AND THEIR USE SILENCE THERAPEUTICS AG (DE) 2010-03-11 — — US claimed
WO-2006069782-A9 LIPID COMPLEXES COATED WITH PEG AND THEIR USE SILENCE THERAPEUTICS AG (DE) 2009-04-30 — — WO claimed
US-20090074852-A1 LIPOPLEX FORMULATIONS FOR SPECIFIC DELIVERY TO VASCULAR ENDOTHELIUM SILENCE THERAPEUTICS AG (DE) 2009-03-19 — — US claimed
EP-2007356-A1 LIPOPLEX FORMULATIONS FOR SPECIFIC DELIVERY TO VASCULAR ENDOTHELIUM Silence Therapeutics AG (DE) 2008-12-31 — — EP claimed
US-20080274116-A1 Lipids, Lipid Complexes and Use Thereof SILENCE THERAPEUTICS AG (DE) 2008-11-06 — — US claimed
JP-2007536324-A — — 2007-12-13 — — JP claimed
WO-2007121947-A1 LIPOPLEX FORMULATIONS FOR SPECIFIC DELIVERY TO VASCULAR ENDOTHELIUM SILENCE THERAPEUTICS AG. (DE) 2007-11-01 — — WO claimed
EP-1771206-A2 LIPIDS, LIPID COMPLEXES AND USE THEREOF atugen AG (DE) 2007-04-11 — — EP claimed
WO-2005105152-A2 LIPIDS, LIPID COMPLEXES AND USE THEREOF ATUGEN AG (DE) 2005-11-10 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090074852-A1 LIPOPLEX FORMULATIONS FOR SPECIFIC DELIVERY TO VASCULAR ENDOTHELIUM LIPG, LIPA, PHOSPHO1 PLA2G2C 83/4885LPAR1 11/4885LPAR3 20/4885
US-12453739-B2 Synergistic enhancement of the delivery of nucleic acids via blended formulations HNRNPAB, FABP1, SNRPE PLA2G2C 296/4885LPAR1 123/4885LPAR3 143/4885
US-12569572-B2 Messenger RNA therapy for the treatment of Friedreich's ataxia SMN1; SMN2, CDR2, ATXN2 PLA2G2C 423/4885LPAR1 1527/4885LPAR3 1093/4885
US-20120065138-A1 LIPIDS, LIPID COMPLEXES AND USE THEREOF MGLL, LIPA, SGMS1 PLA2G2C 470/4885LPAR1 34/4885LPAR3 39/4885
US-12636252-B2 Process of preparing mRNA-loaded lipid nano particles RNMT, SOAT2, METTL16 PLA2G2C 919/4885LPAR1 967/4885LPAR3 1018/4885
US-20100062967-A1 COATED LIPID COMPLEXES AND THEIR USE HDLBP, NR1H3, CETP PLA2G2C 326/4885LPAR1 69/4885LPAR3 108/4885
US-20260115221-A1 SYNERGISTIC ENHANCEMENT OF THE DELIVERY OF NUCLEIC ACIDS VIA BLENDED FORMULATIONS RNMT, PLTP, CHMP4B PLA2G2C 453/4885LPAR1 428/4885LPAR3 510/4885
US-20080274116-A1 Lipids, Lipid Complexes and Use Thereof MGLL, LIPA, SGMS1 PLA2G2C 523/4885LPAR1 32/4885LPAR3 39/4885
US-20250268994-A1 Optimized Nucleotide Sequences Encoding the Extracellular Domain of Human ACE2 Protein or a Portion Thereof ACE2, LNPEP, ACE PLA2G2C 235/4885LPAR1 747/4885LPAR3 671/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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