Dimethylamine

Dimethylamine

SCHEMBL447384

CNC.NCCCOC(=O)CN

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.42
HTR2C P28335 1/20 0.42
NAAA Q02083 1/20 0.38
EPHX1 P07099 1/20 0.35
FAAH O00519 1/20 0.35
PAOX Q6QHF9 3/20 0.33
ALDH1A1 P00352 2/20 0.33
MAPT P10636 1/20 0.33
THRB P10828 1/20 0.33
CNR1 P21554 1/20 0.33
DGKA P23743 1/20 0.33
KDM4E B2RXH2 1/20 0.33
LMNA P02545 1/20 0.33
ODC1 P11926 1/20 0.33
RAD52 P43351 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
CHRM2 P08172 1/20 0.32
CHRM4 P08173 1/20 0.32
CHRM5 P08912 1/20 0.32
CYP2D6 P10635 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL93781 0.91
SCHEMBL18249514 0.84 HTR2C (0.46) CYP1A2HTR2CNAAAFAAHPAOX
SCHEMBL18295865 0.82 HTR2C (0.48) CYP1A2HTR2CNAAAFAAHPAOX
Hydrochloric Acid SCHEMBL29233271 0.82 HTR2C (0.44) CYP1A2HTR2CNAAAFAAHPAOX
SCHEMBL5496994 0.81 HTR2C (0.45) CYP1A2HTR2CNAAAFAAHALDH1A1
SCHEMBL6682800 0.81 HTR2C (0.50) CYP1A2HTR2CNAAAEPHX1FAAH
SCHEMBL20749780 0.81 HTR2C (0.41) HTR2CNAAAEPHX1FAAHALDH1A1
Hydrochloric Acid SCHEMBL28234487 0.79 HTR2C (0.44) CYP1A2HTR2CNAAAFAAHALDH1A1
SCHEMBL3993449 0.77
SCHEMBL175306 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2983678-B1 ANTI-MICROBIAL COMPOSITION ARETEON PTE LTD (SG) 2019-01-02 EP disclosed
US-20170049679-A1 ORAL AND DENTAL HYGIENE AND CLEANING AGENTS FOR REDUCING TOOTH DISCOLORATION HENKEL AG & CO. KGAA (DE) 2017-02-23 US disclosed
US-20160250139-A1 HAIR TREATMENT AGENTS HAVING SUBSTITUTED SILICONE(S) HENKEL AG & CO. KGAA (DE) 2016-09-01 US disclosed
US-20160015735-A1 ANTI-MICROBIAL COMPOSITION ARETEON PTE LTD (SG) 2016-01-21 US disclosed
US-20150164761-A1 HAIR TREATMENT COMPOSITIONS COMPRISING SELECTED FATTY ACID AMIDES AND SELECTED FRAGRANCES HENKEL AG & CO. KGAA (DE) 2015-06-18 US disclosed
US-20150150775-A1 HAIR TREATMENT COMPOSITIONS COMPRISING SELECTED FRAGRANCES AND SELECTED COMPLEXES OF ACIDIC PROTEIN HYDROLYSATES AND BASIC FATTY ACID AMIDOAMINES HENKEL AG & CO. KGAA (DE) 2015-06-04 US disclosed
US-8999939-B2 Hair treatment agents having low-dose oligopeptides HENKEL AG & CO. KGAA (DE) 2015-04-07 US disclosed
US-20140248230-A1 HAIR CARE TREATMENT AGENT HENKEL AG & CO. KGAA (DE) 2014-09-04 US disclosed
US-20140248228-A1 HAIR TREATMENT COMPOSITION WITH CATIONIC CARE SUBSTANCE AND UV FILTER HENKEL AG & CO. KGAA (DE) 2014-09-04 US disclosed
US-20130216490-A1 HAIR TREATMENT AGENTS HAVING LOW-DOSE OLIGOPEPTIDES HENKEL AG & CO. KGAA (DE) 2013-08-22 US disclosed
WO-2004006869-A1 PRODUCTS COMPRISING A DRY APPLICATOR, AN AQUEOUS PHASE AND A LIPID PHASE JOHNSON & JOHNSON GMBH (DE) 2004-01-22 WO disclosed
WO-2004006880-A1 DRY PRODUCTS COMPRISING AN APPLICATOR AND A WAX PHASE JOHNSON & JOHNSON GMBH (DE) 2004-01-22 WO disclosed
WO-2003005982-A1 PRODUCTS COMPRISING A SHEET AND A LIPID AND AQUEOUS PHASE JOHNSON & JOHNSON GMBH (DE) 2003-01-23 WO disclosed
WO-2003005983-A1 DRY PRODUCTS COMPRISING A SHEET AND TWO PHASES JOHNSON & JOHNSON GMBH (DE) 2003-01-23 WO disclosed
EP-1275370-A1 Products comprising a sheet and a lipid and aqueous phase Johnson and Johnson GmbH (DE) 2003-01-15 EP disclosed
EP-1275371-A1 Dry products comprising a sheet and two phases Johnson and Johnson GmbH (DE) 2003-01-15 EP disclosed
US-5939081-A THICKENING AN OIL-IN-WATER EMULSION BY ADDING A THICKENING AGENT HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1999-08-17 US disclosed
US-5795978-A CONTAINING ALKYL OR ALKENL OLIGOGLYCOSIDE AND FATTY ALCOHOL;COSMETICS, DRUGS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1998-08-18 US disclosed
US-5716418-A OXIDATION HAIR COLOR DYES; NONTOXIC, COLORFASTNESS, ABSORPTION, RECEPTIVITY HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1998-02-10 US disclosed
US-5609650-A HAIR DYES, OXIDATION WITH ATMOSPHERIC OXYGEN HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN 1997-03-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160015735-A1 ANTI-MICROBIAL COMPOSITION CUTA, ALG1, TYR CYP1A2 4776/4885HTR2C 4774/4885NAAA 238/4885
US-20130216490-A1 HAIR TREATMENT AGENTS HAVING LOW-DOSE OLIGOPEPTIDES FOLH1, ENPEP, PSAP CYP1A2 4694/4885HTR2C 2563/4885NAAA 643/4885
US-20160250139-A1 HAIR TREATMENT AGENTS HAVING SUBSTITUTED SILICONE(S) EGFR, CUTA, MSH6 CYP1A2 2232/4885HTR2C 1171/4885NAAA 2169/4885
US-20170049679-A1 ORAL AND DENTAL HYGIENE AND CLEANING AGENTS FOR REDUCING TOOTH DISCOLORATION H1-2, H1-0, H1-5 CYP1A2 2823/4885HTR2C 3876/4885NAAA 478/4885
US-20140248228-A1 HAIR TREATMENT COMPOSITION WITH CATIONIC CARE SUBSTANCE AND UV FILTER MC1R, POLR1C, CUTA CYP1A2 4099/4885HTR2C 701/4885NAAA 3891/4885
US-20150164761-A1 HAIR TREATMENT COMPOSITIONS COMPRISING SELECTED FATTY ACID AMIDES AND SELECTED FRAGRANCES FAAH2, FAAH, FADS1 CYP1A2 306/4885HTR2C 760/4885NAAA 26/4885
US-20150150775-A1 HAIR TREATMENT COMPOSITIONS COMPRISING SELECTED FRAGRANCES AND SELECTED COMPLEXES OF ACIDIC PROTEIN HYDROLYSATES AND BASIC FATTY ACID AMIDOAMINES CUTA, FAAH2, FAAH CYP1A2 3911/4885HTR2C 944/4885NAAA 4/4885
US-20140248230-A1 HAIR CARE TREATMENT AGENT H1-4, H1-0, H1-10 CYP1A2 1571/4885HTR2C 2114/4885NAAA 1007/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.