Sugi Predict

Sugi Predict / Compounds / SCHEMBL4472735

SCHEMBL4472735

SCHEMBL4472735

CC(=O)Nc1ccc(S(=O)(=O)NC(=O)c2ccccc2C(F)(F)F)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 2/20 0.53
▸ HTT P42858 2/20 0.53
▸ IDO1 P14902 2/20 0.52
▸ KDM4E B2RXH2 1/20 0.51
▸ BDKRB1 P46663 4/20 0.50
▸ AVPR2 P30518 1/20 0.50
▸ GPR27 Q9NS67 1/20 0.50
▸ CA1 P00915 1/20 0.50
▸ CA2 P00918 1/20 0.50
▸ MMP1 P03956 1/20 0.50
▸ MMP2 P08253 1/20 0.50
▸ MMP9 P14780 1/20 0.50
▸ MMP8 P22894 1/20 0.50
▸ MMP13 P45452 1/20 0.50
▸ FLT1 P17948 2/20 0.49
▸ FLT4 P35916 2/20 0.49
▸ KDR P35968 2/20 0.49
▸ MAPT P10636 1/20 0.49
▸ POLB P06746 2/20 0.49
▸ GAA P10253 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10633856 0.84 HPGD (0.65) ALDH1A1KDM4EFLT1FLT4KDR
SCHEMBL4484204 0.83 RBP4 (0.49) ALDH1A1AVPR2GPR27FLT1FLT4
SCHEMBL14607436 0.83 ALDH1A1 (0.59) ALDH1A1HTTIDO1KDM4EBDKRB1
SCHEMBL4463047 0.82 AVPR2 (0.52) ALDH1A1HTTIDO1KDM4EBDKRB1
SCHEMBL4476646 0.82 FLT1 (0.72) ALDH1A1HTTIDO1BDKRB1CA1
SCHEMBL15449709 0.82 ALDH1A1 (0.76) ALDH1A1HTTIDO1KDM4EBDKRB1
SCHEMBL10223118 0.79 NPC1 (0.56) ALDH1A1HTTIDO1KDM4EBDKRB1
SCHEMBL9967797 0.77 CA1 (0.64) ALDH1A1IDO1KDM4EBDKRB1CA1
SCHEMBL27529841 0.77 SMN1; SMN2 (0.54) IDO1BDKRB1POLBGAAMEN1
SCHEMBL12459275 0.76 TDP1 (0.51) ALDH1A1KDM4EFLT1FLT4KDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7605111-B2 Herbicides SYNGENTA CROP PROTECTION, INC. (US) 2009-10-20 — — US disclosed
US-7459414-B2 Herbicides SYNGENTA CROP PROTECTION, INC. (US) 2008-12-02 — — US disclosed
US-20080200336-A1 HERBICIDAL COMPOSITION SYNEGENTA CROP PROTECTION, INC. (US) 2008-08-21 — — US disclosed
CN-1272324-C Novel herbicides SYNGENTA PARTICIPATIONS AG (CH) 2006-08-30 — — CN disclosed
EP-1481970-B1 Novel herbicides SYNGENTA PARTICIPATIONS AG (CH) 2006-03-22 — — EP disclosed
US-6962894-B1 comprise a herbicide and a safener (counter-agent, antidote) and protect the useful plants, but not the weeds, against the phytotoxic action of the herbicide SYNGENTA CROP PROTECTION, INC. (US) 2005-11-08 — — US disclosed
US-20050187110-A1 mixtures with plant safening agents used for selectively controlling weeds and grasses in crops of useful plants MAETZKE THOMAS (CH) 2005-08-25 — — US disclosed
US-20050164886-A1 Herbicidal compositions ALSONS CORPORATION 2005-07-28 — — US disclosed
US-20050164883-A1 agronomically tolerable salts, isomers and enantiomers of those compounds, are suitable for use as herbicides MAETZKE THOMAS (CH) 2005-07-28 — — US disclosed
US-6894005-B1 Heterocyclic compound containing phenyl groups; postemergence herbicides SYNGENTA CROP PROTECTION, INC. (US) 2005-05-17 — — US disclosed
US-20050090399-A1 Phenyl substituted heterocyclic compounds useful as herbicides FRIEDMANN ADRIAN A (GB) 2005-04-28 — — US disclosed
EP-1481970-A1 Novel herbicides Syngenta Participations AG (CH) 2004-12-01 — — EP disclosed
EP-1210333-B1 p-Tolyl-heterocycles as herbicides SYNGENTA PARTICIPATIONS AG (CH) 2004-11-17 — — EP disclosed
EP-1468000-A1 PHENYL SUBSTITUTED HETEROCYCLIC COMPOUNDS USEFUL AS HERBICIDES Syngenta Participations AG (CH) 2004-10-20 — — EP disclosed
CN-1514829-A Novel herbicides �����ɷ� 2004-07-21 — — CN disclosed
WO-2003062244-A1 PHENYL SUBSTITUTED HETEROCYCLIC COMPOUNDS USEFUL AS HERBICIDES SYNGENTA PARTICIPATIONS AG (CH) 2003-07-31 — — WO disclosed
EP-1210333-A2 NOVEL HERBICIDES Syngenta Participations AG (CH) 2002-06-05 — — EP disclosed
EP-1209975-A1 HERBICIDAL COMPOSITION Syngenta Participations AG (CH) 2002-06-05 — — EP disclosed
WO-2001017972-A2 NOVEL HERBICIDES SYNGENTA PARTICIPATIONS AG (CH) 2001-03-15 — — WO disclosed
WO-2001017353-A1 HERBICIDAL COMPOSITION SYNGENTA PARTICIPATIONS AG (CH) 2001-03-15 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050164886-A1 Herbicidal compositions CBR3, CBR1, CNPY2 ALDH1A1 2814/4885HTT 4002/4885IDO1 3426/4885
US-20050164883-A1 agronomically tolerable salts, isomers and enantiomers of those compounds, are suitable for use as herbicides DDT, SULT2A1, GSTA1 ALDH1A1 65/4885HTT 212/4885IDO1 577/4885
US-20080200336-A1 HERBICIDAL COMPOSITION MTX2, DDT, AGPS ALDH1A1 599/4885HTT 873/4885IDO1 608/4885
US-20050090399-A1 Phenyl substituted heterocyclic compounds useful as herbicides DDT, PAH, CYP1A1 ALDH1A1 35/4885HTT 437/4885IDO1 241/4885
US-20050187110-A1 mixtures with plant safening agents used for selectively controlling weeds and grasses in crops of useful plants PIN1, GMDS, DDT ALDH1A1 345/4885HTT 981/4885IDO1 623/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.