Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4481064 | 0.79 | RNPEP (0.35) | ALDH1A1RNPEP | |
| SCHEMBL137238 | 0.71 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL8631296 | 0.60 | RNPEP (0.35) | ALDH1A1RNPEP | |
| SCHEMBL12987584 | 0.60 | CA4 (0.31) | — | |
| Potassium Ion SCHEMBL11582872 | 0.60 | — | — | |
| Potassium Ion SCHEMBL2453680 | 0.60 | RNPEP (0.39) | ALDH1A1RNPEP | |
| SCHEMBL5614525 | 0.59 | GGT1 (0.52) | ALDH1A1RNPEP | |
| SCHEMBL11192504 | 0.59 | NOS1 (0.33) | ALDH1A1RNPEP | |
| Desmeninol SCHEMBL1685415 | 0.59 | RNPEP (0.43) | ALDH1A1RNPEP | |
| SCHEMBL1624320 | 0.59 | RNPEP (0.38) | ALDH1A1RNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2173700-B1 | METHOD FOR THE PRODUCTION OF KETOACIDS AND THEIR DERIVATIVES | EVONIK DEGUSSA GMBH (DE) | 2015-01-28 | — | — | EP | disclosed |
| US-8299293-B2 | Process for preparing α-keto acids and derivatives thereof | EVONIK DEGUSSA GMBH (DE) | 2012-10-30 | — | — | US | disclosed |
| US-20090076302-A1 | PROCESS FOR PREPARING a-KETO ACIDS AND DERIVATIVES THEREOF | EVONIK DEGUSSA GMBH (DE) | 2009-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090076302-A1 | PROCESS FOR PREPARING a-KETO ACIDS AND DERIVATIVES THEREOF | BCKDK, KHK, ADSL | ALDH1A1 91/4885RNPEP 585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.