Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 3/20 | 0.31 |
| ▸ | THRB | P10828 | 3/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | PTP4A1 | Q93096 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28099813 | 0.86 | MAPT (0.41) | MAPTHPGDHSD17B10TDP1THRB | |
| SCHEMBL30004700 | 0.76 | THRB (0.35) | MAPTHSD17B10GABRA1GABRB1TDP1 | |
| SCHEMBL448738 | 0.76 | THRB (0.35) | MAPTHSD17B10GABRA1GABRB1TDP1 | |
| SCHEMBL7065852 | 0.74 | GPR35 (0.40) | MAPTHSD17B10GABRA1GABRB1TDP1 | |
| SCHEMBL28090715 | 0.72 | PTPN1 (0.32) | MAPTHPGD | |
| SCHEMBL7066275 | 0.68 | GABRA1 (0.38) | HSD17B10GABRA1GABRB1TDP1THRA | |
| SCHEMBL7066995 | 0.67 | GABRA1 (0.33) | GABRA1GABRB1LMNAALOX15ALOX12 | |
| SCHEMBL7066709 | 0.67 | MEN1 (0.43) | GABRA1GABRB1THRATHRBALOX15 | |
| SCHEMBL7067636 | 0.67 | THRB (0.38) | MAPTHSD17B10GABRA1GABRB1THRA | |
| SCHEMBL7066987 | 0.67 | THRB (0.38) | MAPTTDP1THRATHRBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1109776-B1 | BROMINATED MATERIALS | MINNESOTA MINING & MFG (US) | 2003-06-04 | — | — | EP | claimed |
| US-6359170-B1 | Brominated materials | 3M INNOVATIVE PROPERTIES COMPANY | 2002-03-19 | — | — | US | claimed |
| EP-1109776-A1 | BROMINATED MATERIALS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2001-06-27 | — | — | EP | claimed |
| WO-2000014050-A1 | BROMINATED MATERIALS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2000-03-16 | — | — | WO | claimed |
| EP-1109776-B1 | BROMINATED MATERIALS | MINNESOTA MINING & MFG (US) | 2003-06-04 | — | — | EP | disclosed |
| US-6533959-B2 | Formed from monomers such as 2-(4,6-dibromo-2-isopropyl phenoxy)ethyl acrylate; high index of refraction, useful to control flow and intensity of light | 3M INNOVATIVE PROPERTIES COMPANY | 2003-03-18 | — | — | US | disclosed |
| US-20020123590-A1 | Brominated materials | 3M INNOVATIVE PROPERTIES COMPANY | 2002-09-05 | — | — | US | disclosed |
| US-6359170-B1 | Brominated materials | 3M INNOVATIVE PROPERTIES COMPANY | 2002-03-19 | — | — | US | disclosed |
| EP-1109776-A1 | BROMINATED MATERIALS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2001-06-27 | — | — | EP | disclosed |
| WO-2000014050-A1 | BROMINATED MATERIALS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2000-03-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020123590-A1 | Brominated materials | PBRM1, TUBB3, TUBB | MAPT 485/4885HPGD 2021/4885HSD17B10 2133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.