Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 3/20 | 0.38 |
| ▸ | LDHB | P07195 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | BRS3 | P32247 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4494581 | 0.86 | ESR1 (0.38) | LDHALDHBALOX5KMT2AMEN1 | |
| SCHEMBL4482572 | 0.86 | PPARG (0.41) | PPARGPPARAL3MBTL1MMEALOX5 | |
| SCHEMBL4485206 | 0.81 | ALDH1A1 (0.32) | LDHALDHBL3MBTL1KMT2AMEN1 | |
| SCHEMBL4559834 | 0.81 | PPARG (0.41) | LDHALDHBPPARGPPARAL3MBTL1 | |
| SCHEMBL4485668 | 0.81 | ALDH1A1 (0.39) | FNTAFNTB | |
| SCHEMBL4492334 | 0.80 | TAAR1 (0.36) | LDHALDHBALOX5KMT2AMEN1 | |
| SCHEMBL4481909 | 0.79 | KDM4E (0.40) | LDHALDHBL3MBTL1KMT2AMEN1 | |
| SCHEMBL4490045 | 0.79 | PPARG (0.42) | LDHAPPARGPPARABRS3KMT2A | |
| SCHEMBL4504906 | 0.78 | MEN1 (0.45) | L3MBTL1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL4477477 | 0.75 | TDP1 (0.42) | L3MBTL1MMEKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7504429-B2 | Tyrosine kinase inhibitors | MERCK & CO., INC. (US) | 2009-03-17 | — | — | US | claimed |