Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 5/20 | 0.42 |
| ▸ | EPHA2 | P29317 | 9/20 | 0.41 |
| ▸ | KDR | P35968 | 8/20 | 0.41 |
| ▸ | EPHB4 | P54760 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4504899 | 0.92 | EPHA2 (0.45) | HPGDMEN1LMNAMAPTKMT2A | |
| SCHEMBL4496434 | 0.84 | LOXL2 (0.46) | HPGDMEN1LMNAMAPTKMT2A | |
| SCHEMBL4505025 | 0.84 | ALDH1A1 (0.51) | HPGDMEN1LMNAMAPTKMT2A | |
| Hydrochloric Acid SCHEMBL4492473 | 0.78 | PDK1 (0.41) | DRD4EPHA2KDREPHB4 | |
| SCHEMBL4497031 | 0.76 | TCF4 (0.47) | HPGDMEN1LMNAMAPTKMT2A | |
| Hydrochloric Acid SCHEMBL4505071 | 0.76 | DRD4 (0.46) | MEN1LMNAMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL4506389 | 0.75 | MEN1 (0.45) | HPGDMEN1LMNAMAPTKMT2A | |
| SCHEMBL4510657 | 0.75 | PDK1 (0.46) | LMNAMAPTKMT2ADRD4EPHA2 | |
| Hydrochloric Acid SCHEMBL4513041 | 0.75 | DRD4 (0.44) | LMNAMAPTSMN1; SMN2DRD4EPHA2 | |
| SCHEMBL4508306 | 0.75 | ALOX5 (0.46) | HPGDMEN1LMNAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090325956-A1 | Aromatic amine derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325956-A1 | Aromatic amine derivative and use thereof | SCD, SCD5, SMS | HPGD 1447/4885MEN1 4180/4885LMNA 247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.