Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.81 |
| ▸ | GLA | P06280 | 1/20 | 0.81 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.55 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 2/20 | 0.55 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.55 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TNKS | O95271 | 1/20 | 0.55 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butenone SCHEMBL7666350 | 1.00 | TDP1 (0.81) | TDP1GLALMNAMAPTHDAC3 | |
| Butenone SCHEMBL792625 | 0.92 | TDP1 (0.95) | TDP1GLALMNAMAPTHDAC3 | |
| Butenone SCHEMBL5788285 | 0.92 | TDP1 (0.95) | TDP1GLALMNAMAPTHDAC3 | |
| Butenone SCHEMBL2891566 | 0.92 | TDP1 (0.95) | TDP1GLALMNAMAPTHDAC3 | |
| Butenone SCHEMBL4306181 | 0.92 | TDP1 (0.95) | TDP1GLALMNAMAPTHDAC3 | |
| Butenone SCHEMBL6401376 | 0.92 | TDP1 (0.95) | TDP1GLALMNAMAPTHDAC3 | |
| Butenone SCHEMBL7053850 | 0.92 | TDP1 (0.95) | TDP1GLALMNAMAPTHDAC3 | |
| Butenone SCHEMBL29739250 | 0.92 | TDP1 (0.95) | TDP1GLALMNAMAPTHDAC3 | |
| Butenone SCHEMBL699144 | 0.92 | TDP1 (0.95) | TDP1GLALMNAMAPTHDAC3 | |
| Butenone SCHEMBL490740 | 0.92 | TDP1 (0.95) | TDP1GLALMNAMAPTHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090137597-A1 | Novel quinoxalinone derivatives | MSD K.K. (JP) | 2009-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137597-A1 | Novel quinoxalinone derivatives | NDUFB1, NDUFB6, NDUFB7 | TDP1 2781/4885GLA 2386/4885LMNA 976/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.