Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.64 |
| ▸ | TP53 | P04637 | 5/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | THRB | P10828 | 4/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.60 |
| ▸ | PTGES | O14684 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CETP | P11597 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17354449 | 0.71 | THRB (0.68) | MAPTTP53SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL24710856 | 0.71 | THRB (0.70) | MAPTTP53SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL24711164 | 0.71 | PTGES (0.70) | MAPTTP53SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL3456134 | 0.70 | THRB (0.67) | MAPTTP53SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL11576194 | 0.70 | RAB9A (0.59) | MAPTTP53SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL2249921 | 0.69 | MAPT (0.67) | MAPTTP53SMN1; SMN2THRBRXFP1 | |
| SCHEMBL2249546 | 0.69 | NPC1 (0.64) | MAPTTP53SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL15745638 | 0.69 | NPC1 (0.66) | MAPTTP53SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL6231040 | 0.69 | MAPT (0.75) | MAPTTP53SMN1; SMN2HPGDTHRB | |
| SCHEMBL7252808 | 0.69 | PPARG (0.82) | MAPTTP53SMN1; SMN2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090258917-A1 | Benzoxazoles Useful in the Treatment of Inflammation | BIOLIPOX AB (SE) | 2009-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090258917-A1 | Benzoxazoles Useful in the Treatment of Inflammation | IL4I1, EPX, IL4 | MAPT 270/4885TP53 2523/4885SMN1; SMN2 2389/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.