Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | AOC2 | O75106 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SCN4A | P35499 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | G6PD | P11413 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28288419 | 0.84 | MAPT (0.52) | ALDH1A1KDM4EMEN1KMT2AALOX15 | |
| SCHEMBL19563032 | 0.84 | HTR1B (0.51) | ALDH1A1KDM4EMEN1KMT2AALOX15 | |
| SCHEMBL23977878 | 0.82 | ALDH1A1 (0.40) | ALDH1A1KDM4ECYP1A2MEN1KMT2A | |
| SCHEMBL8570866 | 0.82 | PTPN1 (0.41) | ALDH1A1KDM4ECYP1A2MAOAMEN1 | |
| SCHEMBL1710086 | 0.81 | KDM4E (0.45) | ALDH1A1GLAKDM4ECYP1A2AOC2 | |
| SCHEMBL5376369 | 0.81 | MAPT (0.47) | ALDH1A1KDM4ECYP1A2AOC2MAOA | |
| SCHEMBL23977882 | 0.81 | HSP90AA1 (0.39) | ALDH1A1KDM4ECYP1A2MEN1KMT2A | |
| SCHEMBL8083251 | 0.81 | ALDH1A1 (0.48) | ALDH1A1GLAKDM4ECYP1A2AOC2 | |
| SCHEMBL23977889 | 0.80 | SMN1; SMN2 (0.39) | ALDH1A1KDM4ECYP1A2MAOAMEN1 | |
| SCHEMBL10316560 | 0.79 | L3MBTL1 (0.53) | ALDH1A1GLAKDM4ECYP1A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106414429-A | Pyrazole compounds and their use as T-type calcium channel blockers | 埃科特莱茵药品有限公司 | 2017-02-15 | — | — | CN | claimed |
| EP-4310089-A1 | NITROGEN-CONTAINING HETEROCYCLIC POLYCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | Shanghai Hansoh Biomedical Co., Ltd. (CN) | 2024-01-24 | — | — | EP | disclosed |
| US-11693310-B2 | Blue curable resin composition, blue color filter, and display device including same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2023-07-04 | — | — | US | disclosed |
| US-11693310-B2 | Blue curable resin composition, blue color filter, and display device including same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2023-07-04 | — | — | US | disclosed |
| US-11664093-B2 | Extrapolative prediction of enantioselectivity enabled by computer-driven workflow, new molecular representations and machine learning | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2023-05-30 | — | — | US | disclosed |
| WO-2021131835-A1 | COLORED RESIN COMPOSITION | 住友化学株式会社 | 2021-07-01 | — | — | WO | disclosed |
| WO-2021131834-A1 | COLORED RESIN COMPOSITION | 住友化学株式会社 | 2021-07-01 | — | — | WO | disclosed |
| WO-2021039491-A1 | COLORED RESIN COMPOSITION | 住友化学株式会社 | 2021-03-04 | — | — | WO | disclosed |
| US-20200371435-A1 | BLUE CURABLE RESIN COMPOSITION, BLUE COLOR FILTER, AND DISPLAY DEVICE INCLUDING SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2020-11-26 | — | — | US | disclosed |
| WO-2019195159-A1 | PRODRUGS OF FUSED-BICYCLIC C5aR ANTAGONISTS | CHEMOCENTRYX, INC. (US) | 2019-10-10 | — | — | WO | disclosed |
| US-20090234117-A1 | Pyrazolopyrimidine Derivative | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-09-17 | — | — | US | disclosed |
| CN-101516817-A | Process for the preparation of trifluoroethoxytoluenes | GRINDEKS JSC (LV) | 2009-08-26 | — | — | CN | disclosed |
| CN-101516817-A | Process for the preparation of trifluoroethoxytoluenes | GRINDEKS JSC (LV) | 2009-08-26 | — | — | CN | disclosed |
| CN-101516845-A | Preparation method of 2, 5-bis (2,2, 2-trifluoroethoxy) -N- (2-piperidylmethyl) -benzamide and salt thereof | GRINDEKS JSC (LV) | 2009-08-26 | — | — | CN | disclosed |
| EP-2079674-A1 | PROCESS FOR THE PREPARATION OF TRIFLUOROETHOXYTOLUENES | Grindeks, a joint stock company (LV) | 2009-07-22 | — | — | EP | disclosed |
| WO-2008055849-A1 | PROCESS FOR THE PREPARATION OF TRIFLUOROETHOXYTOLUENES | GRINDEKS, A JOINT STOCK COMPANY (LV) | 2008-05-15 | — | — | WO | disclosed |
| EP-1903045-A1 | PYRAZOLOPYRIMIDINE DERIVATIVE | Mitsubishi Tanabe Pharma Corporation (JP) | 2008-03-26 | — | — | EP | disclosed |
| US-20070219216-A1 | 1-Alkylpiperazinyl-Pyrrolidin-2,5-Dione Derivatives as Adrenergic Receptor Antagonists | RANBAXY LABORATORIES LIMITED (IN) | 2007-09-20 | — | — | US | disclosed |
| US-20070219216-A1 | 1-Alkylpiperazinyl-Pyrrolidin-2,5-Dione Derivatives as Adrenergic Receptor Antagonists | RANBAXY LABORATORIES LIMITED (IN) | 2007-09-20 | — | — | US | disclosed |
| US-7196197-B2 | Process for the preparation of Flecainide, its pharmaceutically acceptable salts and important intermediates thereof | APOTEX PHARMACHEM INC. | 2007-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090234117-A1 | Pyrazolopyrimidine Derivative | MC2R, CRHR1, AVPR2 | ALDH1A1 1328/4885GLA 4864/4885KDM4E 3600/4885 |
| US-20070219216-A1 | 1-Alkylpiperazinyl-Pyrrolidin-2,5-Dione Derivatives as Adrenergic Receptor Antagonists | ADRA1D, ADRA1A, ADRB1 | ALDH1A1 51/4885GLA 2202/4885KDM4E 3759/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.