Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | CDK4 | P11802 | 7/20 | 0.43 |
| ▸ | CCND1 | P24385 | 7/20 | 0.43 |
| ▸ | CDK2 | P24941 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13586012 | 0.93 | HDAC1 (0.47) | CDK4CCND1CDK2LMNAALDH1A1 | |
| SCHEMBL4351462 | 0.83 | HTR1A (0.40) | KMT2ALMNAALDH1A1MEN1HTR1A | |
| SCHEMBL4351631 | 0.79 | ALDH1A1 (0.40) | KMT2ALMNAALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL4353770 | 0.79 | NPY2R (0.42) | ALDH1A1HTR1A | |
| SCHEMBL4538463 | 0.78 | NPY2R (0.39) | LMNAALDH1A1HTR1A | |
| SCHEMBL13586042 | 0.78 | CYP3A4 (0.38) | LMNAALDH1A1MAPTSMN1; SMN2HTR1A | |
| SCHEMBL13586274 | 0.76 | CTSC (0.36) | LMNAHTR1AHTR2C | |
| SCHEMBL13586016 | 0.75 | SMN1; SMN2 (0.43) | KMT2ALMNAALDH1A1MEN1GAA | |
| SCHEMBL4360506 | 0.74 | GPR119 (0.47) | — | |
| SCHEMBL4352115 | 0.68 | GPR119 (0.46) | KMT2AALDH1A1MEN1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | claimed |