Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.47 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | TACR3 | P29371 | 1/20 | 0.42 |
| ▸ | CDK4 | P11802 | 7/20 | 0.40 |
| ▸ | CCND1 | P24385 | 7/20 | 0.40 |
| ▸ | CDK2 | P24941 | 3/20 | 0.40 |
| ▸ | ECE1 | P42892 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4532282 | 0.93 | GLA (0.46) | HDAC1CDK4CCND1CDK2HTR1A | |
| SCHEMBL13586274 | 0.82 | CTSC (0.36) | HTR1AHTR2CLMNA | |
| SCHEMBL4353770 | 0.81 | NPY2R (0.42) | HTR1AALDH1A1 | |
| SCHEMBL4351462 | 0.81 | HTR1A (0.40) | HTR1ACYP2D6ALDH1A1LMNA | |
| SCHEMBL4355465 | 0.80 | HTR1A (0.35) | HTR1ACYP2D6ALDH1A1LMNA | |
| SCHEMBL4538463 | 0.80 | NPY2R (0.39) | HTR1ACYP2D6ALDH1A1LMNA | |
| SCHEMBL13586016 | 0.79 | SMN1; SMN2 (0.43) | HTR2BALDH1A1MAPTRAB9ALMNA | |
| SCHEMBL13586042 | 0.79 | CYP3A4 (0.38) | HTR1ACYP2D6ALDH1A1MAPTLMNA | |
| SCHEMBL4541603 | 0.78 | GPR142 (0.48) | OPRK1CYP2D6 | |
| SCHEMBL4351631 | 0.77 | ALDH1A1 (0.40) | HTR1AALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |