Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | NPY2R | P49146 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13586042 | 0.92 | CYP3A4 (0.38) | ALDH1A1SMN1; SMN2LMNATSHRMCHR1 | |
| SCHEMBL4351462 | 0.91 | HTR1A (0.40) | ALDH1A1KMT2ALMNAMEN1TSHR | |
| SCHEMBL4355465 | 0.88 | HTR1A (0.35) | ALDH1A1LMNATSHRMCHR1HTR1A | |
| SCHEMBL4364150 | 0.84 | NAAA (0.35) | ALDH1A1HTR1AKCNH2HRH3NPY2R | |
| SCHEMBL4538463 | 0.84 | NPY2R (0.39) | ALDH1A1LMNATSHRMCHR1HTR1A | |
| SCHEMBL4353770 | 0.83 | NPY2R (0.42) | ALDH1A1MCHR1HTR1AKCNH2HRH3 | |
| SCHEMBL13586035 | 0.82 | NPY2R (0.32) | HTR1AKCNH2HRH3NPY2R | |
| SCHEMBL4357646 | 0.82 | FKBP1A (0.43) | ALDH1A1KMT2ASMN1; SMN2LMNAMEN1 | |
| SCHEMBL4350045 | 0.82 | MCHR1 (0.38) | MCHR1KCNH2 | |
| SCHEMBL4360506 | 0.81 | GPR119 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |