Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.42 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.39 |
| ▸ | GHSR | Q92847 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4357646 | 0.92 | FKBP1A (0.43) | SMN1; SMN2MAPTALDH1A1LMNAMCHR1 | |
| SCHEMBL4351462 | 0.84 | HTR1A (0.40) | ALDH1A1LMNACYP3A4KCNH2KMT2A | |
| SCHEMBL4355465 | 0.83 | HTR1A (0.35) | ALDH1A1LMNAMCHR1CYP3A4KCNH2 | |
| SCHEMBL4364150 | 0.83 | NAAA (0.35) | ALDH1A1KCNH2HPGDGPR119 | |
| SCHEMBL4541603 | 0.83 | GPR142 (0.48) | MCHR1CYP3A4KMT2AMEN1 | |
| SCHEMBL4538463 | 0.83 | NPY2R (0.39) | ALDH1A1LMNAMCHR1CYP3A4KCNH2 | |
| SCHEMBL4361256 | 0.83 | OPRD1 (0.46) | SMN1; SMN2GAAKMT2AMEN1 | |
| SCHEMBL13586042 | 0.82 | CYP3A4 (0.38) | SMN1; SMN2MAPTALDH1A1LMNAMCHR1 | |
| SCHEMBL13586274 | 0.82 | CTSC (0.36) | LMNAMCHR1KCNH2GPR119 | |
| SCHEMBL4350045 | 0.81 | MCHR1 (0.38) | MCHR1KCNH2GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |