Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 10/20 | 0.75 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.75 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.75 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.75 |
| ▸ | PPARG | P37231 | 2/20 | 0.75 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.75 |
| ▸ | MEN1 | O00255 | 1/20 | 0.75 |
| ▸ | PTGES | O14684 | 1/20 | 0.75 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.75 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.75 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.75 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.75 |
| ▸ | LMNA | P02545 | 1/20 | 0.75 |
| ▸ | ALB | P02768 | 1/20 | 0.75 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.75 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.75 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.75 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.75 |
| ▸ | AR | P10275 | 1/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17384911 | 0.91 | AKR1C3 (0.74) | PTGS2PTGS1AKR1C3AKR1C2PPARG | |
| SCHEMBL23602328 | 0.90 | PTGS2 (0.74) | PTGS2PTGS1AKR1C3AKR1C2PPARG | |
| SCHEMBL4538160 | 0.90 | PTGS2 (0.70) | PTGS2PTGS1AKR1C3AKR1C2PPARG | |
| SCHEMBL4535313 | 0.89 | PTGS2 (0.71) | PTGS2PTGS1AKR1C3AKR1C2PPARG | |
| SCHEMBL15206529 | 0.89 | PTGS2 (0.71) | PTGS2PTGS1AKR1C3AKR1C2PPARG | |
| SCHEMBL4538035 | 0.88 | PTGS1 (0.83) | PTGS2PTGS1AKR1C3AKR1C2PPARG | |
| SCHEMBL860853 | 0.88 | PTGS2 (0.80) | PTGS2PTGS1AKR1C3AKR1C2PPARG | |
| Indomethacin SCHEMBL8813964 | 0.87 | PTGS2 (0.88) | PTGS2PTGS1AKR1C3AKR1C2PPARG | |
| SCHEMBL17385262 | 0.87 | PTGS2 (0.78) | PTGS2PTGS1AKR1C3AKR1C2PPARG | |
| SCHEMBL9040318 | 0.87 | PTGS2 (0.78) | PTGS2PTGS1AKR1C3AKR1C2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12454502-B2 | Synthesis of deuterated aldehydes | ARIZONA BOARD OF REGENTS ON BEHALF OF ATHE UNIVERSITY OF ARIZONA (US) | 2025-10-28 | — | — | US | disclosed |
| WO-2023010200-A1 | THERAPEUTIC COORDINATION POLYMERS CONTAINING PHARMACEUTICALS FOR DRUG RELEASE APPLICATIONS | UNIVERSITY OF WINDSOR (CA) | 2023-02-09 | — | — | WO | disclosed |
| US-20220356139-A1 | SYNTHESIS OF DEUTERATED ALDEHYDES | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA | 2022-11-10 | — | — | US | disclosed |
| US-20220017432-A1 | CONJUGATES DERIVED FROM NON-STEROIDAL ANTI-INFLAMMATORY DRUGS AND METHODS OF USE THEREOF IN IMAGING | Reiley Pharmaceuticals, Inc. | 2022-01-20 | — | — | US | disclosed |
| WO-2021209563-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF VIRAL INFECTIONS BY RESPIRATORY SYNDROME-RELATED CORONAVIRUS | SOM INNOVATION BIOTECH, S.A. (ES) | 2021-10-21 | — | — | WO | disclosed |
| WO-2021045879-A1 | SYNTHESIS OF DEUTERATED ALDEHYDES | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2021-03-11 | — | — | WO | disclosed |
| WO-2021045879-A1 | SYNTHESIS OF DEUTERATED ALDEHYDES | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2021-03-11 | — | — | WO | disclosed |
| EP-3693022-A2 | COX-2-TARGETING, PLATINUM-CONTAINING CONJUGATES AND THEIR USE IN THE TREATMENT OF TUMORS AND CANCERS | Reiley Pharmaceuticals, Inc. (US) | 2020-08-12 | — | — | EP | disclosed |
| EP-3242688-B1 | COX-2-TARGETING, PLATINUM-CONTAINING CONJUGATES AND THEIR USE IN THE TREATMENT OF TUMORS AND CANCERS | REILEY PHARMACEUTICALS INC (US) | 2020-01-29 | — | — | EP | disclosed |
| US-20190169084-A1 | CONJUGATES DERIVED FROM NON-STEROIDAL ANTI-INFLAMMATORY DRUGS AND METHODS OF USE THEREOF IN IMAGING | Reiley Pharmaceuticals, Inc. | 2019-06-06 | — | — | US | disclosed |
| WO-2012063085-A2 | DRUG DERIVATIVES | REDX PHARMA LIMITED (GB) | 2012-05-18 | — | — | WO | disclosed |
| WO-2012063085-A2 | DRUG DERIVATIVES | REDX PHARMA LIMITED (GB) | 2012-05-18 | — | — | WO | disclosed |
| US-7964738-B2 | Pharmaceutical compositions and methods of use of lipophilic, silicon-substituted, cyclooxygenase-2 selective non-steroidal anti-inflammatory drugs and derivatives | SILAMED, INC. (US) | 2011-06-21 | — | — | US | disclosed |
| US-7960544-B2 | Useful indole compounds | IRONWOOD PHARMACEUTICALS, INC. (US) | 2011-06-14 | — | — | US | disclosed |
| US-20090264653-A1 | USEFUL INDOLE COMPOUNDS | IRONWOOD PHARMACEUTICALS, INC. | 2009-10-22 | — | — | US | disclosed |
| US-20080261913-A1 | Phosphoroamidate conjugated to therapeutic agent such as Aclarubicin; nucleoside derivatives; S-pivaloyl-2-thioethyl phosphoroamidate; liver cancer, inflammation, fibrosis, metabolic disorders | IDENIX PHARMACEUTICALS, INC. | 2008-10-23 | — | — | US | disclosed |
| EP-0254354-B1 | PHARMACEUTICALLY USEFUL DERIVATIVES OF THIAZOLIDINE-4-CARBOXYLIC ACID | ZAMBON S.p.A. (IT) | 1993-03-31 | — | — | EP | disclosed |
| US-4840936-A | ANTIFLAMMATORY, ANALGESIC AGENT TO PREVENT ARRHYTHMIAS | ZAMBON S.P.A. (IT) | 1989-06-20 | — | — | US | disclosed |
| EP-0254354-A1 | Pharmaceutically useful derivatives of thiazolidine-4-carboxylic acid | ZAMBON S.p.A. (IT) | 1988-01-27 | — | — | EP | disclosed |
| US-4186133-A | Process for the preparation of an indole-3-acetohydroxamic acid | ISTITUTO BIOLOGICO CHEMIOTERAPICO "ABC" S.P.A. (IT) | 1980-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12454502-B2 | Synthesis of deuterated aldehydes | ADH1C, ADH1A, CBR1 | PTGS2 1584/4885PTGS1 775/4885AKR1C3 148/4885 |
| US-20220017432-A1 | CONJUGATES DERIVED FROM NON-STEROIDAL ANTI-INFLAMMATORY DRUGS AND METHODS OF USE THEREOF IN IMAGING | PTGES3, PTGES, HPGDS | PTGS2 6/4885PTGS1 5/4885AKR1C3 568/4885 |
| US-20190169084-A1 | CONJUGATES DERIVED FROM NON-STEROIDAL ANTI-INFLAMMATORY DRUGS AND METHODS OF USE THEREOF IN IMAGING | PTGES3, PTGES, HPGDS | PTGS2 6/4885PTGS1 5/4885AKR1C3 568/4885 |
| US-20220356139-A1 | SYNTHESIS OF DEUTERATED ALDEHYDES | ADH1C, ADH1A, CBR1 | PTGS2 1584/4885PTGS1 775/4885AKR1C3 148/4885 |
| US-20080261913-A1 | Phosphoroamidate conjugated to therapeutic agent such as Aclarubicin; nucleoside derivatives; S-pivaloyl-2-thioethyl phosphoroamidate; liver cancer, inflammation, fibrosis, metabolic disorders | NTPCR, PNP, TYMP | PTGS2 4118/4885PTGS1 3870/4885AKR1C3 1657/4885 |
| US-20090264653-A1 | USEFUL INDOLE COMPOUNDS | FAAH, FAAH2, AANAT | PTGS2 460/4885PTGS1 363/4885AKR1C3 970/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.