Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 3/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 2/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | WNT1 | P04628 | 1/20 | 0.34 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4403763 | 0.92 | TLR9 (0.42) | GSK3BTLR9PIK3CACD274ATM | |
| SCHEMBL4398653 | 0.90 | MCHR1 (0.37) | GSK3BDYRK1A | |
| SCHEMBL4396957 | 0.89 | TLR9 (0.42) | GSK3BTLR9CD274DYRK1AEGLN1 | |
| SCHEMBL916126 | 0.88 | GSK3B (0.42) | GSK3BTLR9PIK3CACD274DYRK1A | |
| SCHEMBL4410357 | 0.86 | GSK3B (0.40) | GSK3BTLR9PIK3CACD274DYRK1A | |
| SCHEMBL4551165 | 0.81 | SIGMAR1 (0.40) | TLR9CD274DYRK1A | |
| SCHEMBL4401911 | 0.80 | HTR1A (0.38) | HTR7 | |
| SCHEMBL914569 | 0.80 | TLR9 (0.44) | GSK3BTLR9CD274DYRK1AEGLN1 | |
| SCHEMBL4403446 | 0.79 | DYRK1A (0.37) | GSK3BTLR9CD274DYRK1AWNT1 | |
| SCHEMBL4411339 | 0.78 | HTR7 (0.38) | DYRK1AHTR7WNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720859-B1 | CHEMOKINE RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 2009-12-23 | — | — | EP | claimed |