Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4396992 | 0.93 | KMT2A (0.41) | SIGMAR1MCHR1DRD4KMT2ADYRK1A | |
| SCHEMBL4411339 | 0.92 | HTR7 (0.38) | KMT2ADYRK1ADRD2 | |
| SCHEMBL4398653 | 0.91 | MCHR1 (0.37) | SIGMAR1MCHR1DRD4KMT2ADYRK1A | |
| SCHEMBL4541737 | 0.90 | SLC2A1 (0.39) | SIGMAR1MCHR1DRD4PDCD1CD274 | |
| SCHEMBL4403763 | 0.89 | TLR9 (0.42) | PDCD1CD274DYRK1ATLR9 | |
| SCHEMBL914166 | 0.86 | DRD4 (0.44) | MCHR1DRD4KMT2ADYRK1APOLB | |
| SCHEMBL4396457 | 0.85 | HRH3 (0.42) | KMT2ASMN1; SMN2DRD2 | |
| SCHEMBL4410349 | 0.85 | HRH3 (0.42) | KMT2ASMN1; SMN2DRD2 | |
| SCHEMBL4396410 | 0.84 | L3MBTL1 (0.40) | MCHR1DYRK1A | |
| SCHEMBL4405570 | 0.83 | TLR7 (0.43) | SIGMAR1KMT2ADYRK1ASMN1; SMN2TLR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720859-B1 | CHEMOKINE RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 2009-12-23 | — | — | EP | claimed |