Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.40 |
| ▸ | WNT1 | P04628 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 4/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4396337 | 0.92 | HTR7 (0.43) | FAAHKDM4EALDH1A1 | |
| SCHEMBL4396992 | 0.91 | KMT2A (0.41) | MCHR1DYRK1AFAAHKDM4E | |
| SCHEMBL4394199 | 0.91 | CHRM3 (0.41) | WNT1DYRK1AFAAH | |
| SCHEMBL4396457 | 0.90 | HRH3 (0.42) | L3MBTL1FAAHHRH3KDM4EALDH1A1 | |
| SCHEMBL4410349 | 0.90 | HRH3 (0.42) | L3MBTL1FAAHHRH3KDM4EALDH1A1 | |
| SCHEMBL4401571 | 0.90 | HPGDS (0.39) | WNT1DYRK1A | |
| SCHEMBL4406835 | 0.89 | CHRM3 (0.40) | MCHR1WNT1DYRK1AFAAH | |
| SCHEMBL4405570 | 0.88 | TLR7 (0.43) | DYRK1AKDM4ERXFP1HPGDHTT | |
| SCHEMBL4405673 | 0.88 | CHRM3 (0.42) | MCHR1WNT1DYRK1AHRH3 | |
| SCHEMBL4396957 | 0.87 | TLR9 (0.42) | WNT1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720859-B1 | CHEMOKINE RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 2009-12-23 | — | — | EP | claimed |