Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.33 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL455232 | 0.85 | ALDH1A1 (0.39) | ALDH1A1POLBKMT2ACYP1A1CYP1B1 | |
| SCHEMBL6895240 | 0.78 | PTGS2 (0.44) | ALDH1A1POLBKMT2ATAAR1PTGS2 | |
| SCHEMBL509528 | 0.73 | PTGS1 (0.35) | ALDH1A1POLBPTGS2TSHR | |
| SCHEMBL457740 | 0.73 | CA1 (0.35) | ALDH1A1KMT2ANR1I2CYP3A4CA12 | |
| SCHEMBL263267 | 0.70 | NOS3 (0.34) | ALDH1A1TSHR | |
| SCHEMBL147391 | 0.70 | PTGS2 (0.37) | PTGS2CYP1A2CYP2A6 | |
| SCHEMBL508938 | 0.69 | TSHR (0.37) | ALDH1A1TSHR | |
| SCHEMBL9487944 | 0.69 | — | — | |
| SCHEMBL2467446 | 0.69 | — | — | |
| SCHEMBL491150 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0312019-B1 | CONDENSED HETEROCYCLIC COMPOUNDS, A PROCESS FOR PREPARING THE SAME AND A HERBICIDAL COMPOSITION THEREOF | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1993-08-04 | — | — | EP | claimed |
| US-4978385-A | 4-halopyridine-3-carboxamide compounds and herbicidal compositions thereof | DAICEL CHEMICAL INDUSTRIES LTD. (JP) | 1990-12-18 | — | — | US | claimed |
| US-4936121-A | Condensed heterocyclic compounds, a process for preparing the same and a herbicidal composition thereof | DAICEL CHEMICAL INDUSTRIES LTD. (JP) | 1990-06-26 | — | — | US | claimed |
| EP-0312019-A2 | Condensed heterocyclic compounds, a process for preparing the same and a herbicidal composition thereof | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1989-04-19 | — | — | EP | claimed |
| EP-0292990-A1 | 4-Halopyridine-3-carboxamide compounds and herbicidal composition thereof | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1988-11-30 | — | — | EP | claimed |
| EP-3045450-B1 | INTERMEDIATE COMPOUNDS IN PROCESSES FOR PRODUCING PYRIDAZINONE COMPOUNDS | SUMITOMO CHEMICAL CO (JP) | 2018-02-07 | — | — | EP | disclosed |
| CN-104277004-B | Prepare method and its intermediate of pyridazinone compound | 住友化学株式会社 | 2016-08-24 | — | — | CN | disclosed |
| CN-104326952-B | Prepare method and its intermediate of pyridazinone compound | 住友化学株式会社 | 2016-08-24 | — | — | CN | disclosed |
| EP-3045450-A1 | INTERMEDIATE COMPOUNDS IN A PROCESS FOR PRODUCING PYRIDAZINONE COMPOUNDS | SUMITOMO CHEMICAL CO., LTD. (JP) | 2016-07-20 | — | — | EP | disclosed |
| EP-2614053-B1 | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATES THEREOF | SUMITOMO CHEMICAL CO (JP) | 2016-03-23 | — | — | EP | disclosed |
| CN-103180300-B | Process for producing pyridazinone compound and intermediate thereof | SUMITOMO CHEMICAL CO.,LTD. (JP) | 2015-10-07 | — | — | CN | disclosed |
| US-9040709-B2 | Method for producing pyridazinone compounds and intermediate thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-05-26 | — | — | US | disclosed |
| WO-2012033225-A1 | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-03-15 | — | — | WO | disclosed |
| US-20120028988-A1 | USE OF PYRIDAZINONE COMPOUND FOR CONTROL OF HARMFUL ARTHROPOD PESTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-02-02 | — | — | US | disclosed |
| US-20120028803-A1 | PYRIDAZINONE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-02-02 | — | — | US | disclosed |
| EP-2188264-B1 | PYRIDAZINONE COMPOUND AND HERBICIDE CONTAINING THE SAME | SUMITOMO CHEMICAL CO (JP) | 2011-03-23 | — | — | EP | disclosed |
| US-20100327216-A1 | MICROCAPSULES, THEIR PREPARATION AND USE | BASF SE (DE) | 2010-12-30 | — | — | US | disclosed |
| EP-2262863-A2 | MICROCAPSULES, PRODUCTION AND USE THEREOF | BASF SE (DE) | 2010-12-22 | — | — | EP | disclosed |
| US-20100216642-A1 | PYRIDAZINONE COMPOUND AND HERBICIDE CONTAINING THE SAME | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-08-26 | — | — | US | disclosed |
| WO-2009112378-A2 | MICROCAPSULES, PRODUCTION AND USE THEREOF | BASF SE (DE) | 2009-09-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120028803-A1 | PYRIDAZINONE COMPOUND AND USE THEREOF | C5, C1S, WEE1 | ALDH1A1 1534/4885POLB 3763/4885KMT2A 4005/4885 |
| US-20100216642-A1 | PYRIDAZINONE COMPOUND AND HERBICIDE CONTAINING THE SAME | WEE1, WEE2, CBR3 | ALDH1A1 273/4885POLB 3977/4885KMT2A 1764/4885 |
| US-20120028988-A1 | USE OF PYRIDAZINONE COMPOUND FOR CONTROL OF HARMFUL ARTHROPOD PESTS | PLPBP, PNPO, PIR | ALDH1A1 1293/4885POLB 2021/4885KMT2A 2737/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.