Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.51 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8744900 | 0.79 | HPGD (0.81) | LMNAKDM4EHPGDL3MBTL1GAA | |
| SCHEMBL1093862 | 0.78 | HPGD (0.91) | LMNAKDM4EHPGDL3MBTL1GAA | |
| SCHEMBL17578483 | 0.78 | TSHR (0.40) | LMNAKDM4EL3MBTL1TSHRMEN1 | |
| SCHEMBL2584078 | 0.77 | IDO1 (0.47) | L3MBTL1MEN1KMT2A | |
| SCHEMBL4582261 | 0.77 | NAAA (0.56) | LMNAHPGDGAAPOLBHDAC1 | |
| SCHEMBL2187602 | 0.77 | HPGD (1.00) | LMNAKDM4EHPGDL3MBTL1GAA | |
| SCHEMBL6290032 | 0.76 | L3MBTL1 (0.72) | LMNAKDM4EHPGDL3MBTL1GAA | |
| SCHEMBL9829299 | 0.76 | LMNA (0.77) | LMNAKDM4EHPGDL3MBTL1GAA | |
| SCHEMBL6289079 | 0.76 | L3MBTL1 (0.72) | LMNAKDM4EHPGDL3MBTL1GAA | |
| SCHEMBL2186352 | 0.76 | HDAC2 (0.72) | LMNAKDM4EHPGDL3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080317685-A1 | Photoprotective cosmetic compositions comprising photostabilized dibenzoylmethane compounds and siloxane-containing arylalkyl benzoate amide compounds | L'OREAL (FR) | 2008-12-25 | — | — | US | disclosed |
| US-20080317685-A1 | Photoprotective cosmetic compositions comprising photostabilized dibenzoylmethane compounds and siloxane-containing arylalkyl benzoate amide compounds | L'OREAL (FR) | 2008-12-25 | — | — | US | disclosed |
| EP-1925289-A2 | Cosmetic composition containing a dibenzoylmethane derivative and a siloxanic benzoate arylalkyl amide derivative; method for photostabilising the dibenzoylmethane derivative | L'Oréal (FR) | 2008-05-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080317685-A1 | Photoprotective cosmetic compositions comprising photostabilized dibenzoylmethane compounds and siloxane-containing arylalkyl benzoate amide compounds | AADAC, DDT, CUTA | LMNA 1962/4885KDM4E 759/4885HPGD 827/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.