Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL547503 | 0.94 | BCHE (0.38) | LMNATDP1ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL31072151 | 0.94 | BCHE (0.38) | LMNATDP1ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL3759626 | 0.85 | TSHR (0.35) | LMNAACHE | |
| SCHEMBL6761317 | 0.82 | TDP1 (0.39) | LMNATDP1ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL6036449 | 0.78 | CA1 (0.33) | — | |
| SCHEMBL5829971 | 0.78 | FABP4 (0.38) | LMNATDP1ALDH1A1GAA | |
| SCHEMBL137132 | 0.77 | HTR6 (0.46) | LMNATDP1ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL4861374 | 0.77 | RAPGEF4 (0.40) | LMNATDP1ALDH1A1SMN1; SMN2POLB | |
| P-Xylene SCHEMBL3404430 | 0.76 | GAA (0.46) | LMNATDP1ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL3127290 | 0.76 | CA12 (0.40) | LMNATDP1ALDH1A1SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1509814-A4 | ACETAL PROTECTED POLYMERS AND PHOTORESISTS COMPOSITIONS THEREOF | FUJIFILM ELECTRONIC MATERIALS (US) | 2008-08-27 | — | — | EP | disclosed |
| EP-1885819-A2 | PRETREATMENT COMPOSITIONS | FujiFilm Electronic Materials USA, Inc. (US) | 2008-02-13 | — | — | EP | disclosed |
| WO-2006132906-A2 | PRETREATMENT COMPOSITIONS | FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) | 2006-12-14 | — | — | WO | disclosed |
| EP-1509814-A2 | ACETAL PROTECTED POLYMERS AND PHOTORESISTS COMPOSITIONS THEREOF | Arch Specialty Chemicals, Inc. (US) | 2005-03-02 | — | — | EP | disclosed |
| WO-2003099782-A2 | ACETAL PROTECTED POLYMERS AND PHOTORESISTS COMPOSITIONS THEREOF | ARCH SPECIALTY CHEMICALS, INC. (US) | 2003-12-04 | — | — | WO | disclosed |