Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 1/20 | 0.33 |
| ▸ | ARG2 | P78540 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 4/20 | 0.33 |
| ▸ | OTC | P00480 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 4/20 | 0.32 |
| ▸ | NOS3 | P29474 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4586374 | 0.88 | TLR2 (0.32) | ARG1ARG2 | |
| SCHEMBL4587971 | 0.81 | ALDH1A1 (0.36) | — | |
| SCHEMBL4589462 | 0.81 | NOD1 (0.41) | — | |
| SCHEMBL4586128 | 0.79 | CA12 (0.35) | ARG1ARG2NOS1NOS2NOS3 | |
| SCHEMBL4588024 | 0.78 | BHMT (0.33) | ARG1ARG2NOS1NOS2NOS3 | |
| SCHEMBL4618533 | 0.77 | PTGS1 (0.33) | ARG1ARG2 | |
| SCHEMBL4587301 | 0.76 | ARG1 (0.35) | ARG1ARG2NOS1NOS2NOS3 | |
| SCHEMBL4587534 | 0.76 | ALDH1A1 (0.34) | ARG1ARG2NOS1NOS2NOS3 | |
| SCHEMBL5148890 | 0.75 | OTC (0.43) | NOS1OTCNOS2NOS3 | |
| SCHEMBL9497864 | 0.73 | DPP7 (0.37) | NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080287407-A1 | Nitric Oxide Releasing Pyruvate Compounds, Compositions and Methods of Use | NITROMED, INC. (US) | 2008-11-20 | — | — | US | claimed |
| US-20080287407-A1 | Nitric Oxide Releasing Pyruvate Compounds, Compositions and Methods of Use | NITROMED, INC. (US) | 2008-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287407-A1 | Nitric Oxide Releasing Pyruvate Compounds, Compositions and Methods of Use | PC, PDK1, NOS3 | ARG1 73/4885ARG2 19/4885NOS1 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.