Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | ANPEP | P15144 | 2/20 | 0.33 |
| ▸ | IL1RN | P18510 | 1/20 | 0.33 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.33 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL454919 | 0.80 | ESR2 (0.35) | ALDH1A1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL456741 | 0.79 | KDM4E (0.31) | ALDH1A1ANPEPKDM4EMEN1MAPT | |
| SCHEMBL457353 | 0.75 | PDE4D (0.33) | ALDH1A1MAPTNPSR1HRH1 | |
| SCHEMBL457364 | 0.72 | ALDH1A1 (0.44) | ALDH1A1MAPK1MAPTHPGDHSD17B10 | |
| SCHEMBL454901 | 0.69 | ALDH1A1 (0.41) | ALDH1A1MAPK1MAPTHPGDHSD17B10 | |
| SCHEMBL457524 | 0.69 | ALDH1A1 (0.41) | ALDH1A1MAPK1KDM4EHPGDNPSR1 | |
| SCHEMBL457102 | 0.66 | ALDH1A1 (0.38) | ALDH1A1MAPK1 | |
| SCHEMBL455777 | 0.64 | RAB9A (0.41) | ALDH1A1MAPK1MEN1KMT2ANPSR1 | |
| SCHEMBL16752251 | 0.64 | AKR1C3 (0.31) | — | |
| SCHEMBL16393627 | 0.62 | BRD4 (0.51) | ALDH1A1MAPK1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2614053-A1 | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2013-07-17 | — | — | EP | disclosed |
| WO-2012033225-A1 | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-03-15 | — | — | WO | disclosed |