Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.56 |
| ▸ | CA1 | P00915 | 3/20 | 0.56 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | PKM | P14618 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | IL1RN | P18510 | 1/20 | 0.54 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 6/20 | 0.50 |
| ▸ | CA9 | Q16790 | 6/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | UQCRB | P14927 | 1/20 | 0.44 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL16267472 | 0.95 | CA2 (0.56) | CA2CA1KEAP1KMT2AMEN1 | |
| SCHEMBL1951008 | 0.95 | CA2 (0.56) | CA2CA1KEAP1KMT2AMEN1 | |
| SCHEMBL28557301 | 0.95 | CA2 (0.56) | CA2CA1KEAP1KMT2AMEN1 | |
| SCHEMBL29755974 | 0.95 | CA2 (0.56) | CA2CA1KEAP1KMT2AMEN1 | |
| SCHEMBL27182687 | 0.82 | UQCRB (0.56) | CA2CA1KEAP1KMT2AMEN1 | |
| SCHEMBL30834782 | 0.78 | CYP19A1 (0.52) | CA2CA1KEAP1KMT2AMEN1 | |
| SCHEMBL2591593 | 0.78 | MGLL (0.50) | CA2CA12CA9 | |
| SCHEMBL6005110 | 0.76 | CA2 (0.64) | CA2CA1KEAP1KMT2AMEN1 | |
| SCHEMBL59151 | 0.76 | KEAP1 (0.64) | CA2CA1KEAP1KMT2AMEN1 | |
| SCHEMBL30834834 | 0.75 | NR3C2 (0.47) | CA2CA1KEAP1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1919439-A2 | PROCESS FOR BLEACHING KERATIN FIBERS | The Procter and Gamble Company (US) | 2008-05-14 | — | — | EP | claimed |
| EP-1919440-A2 | AGENT FOR SIMULTANEOUS LIGHTENING AND COLORING OF KERATIN FIBRES CONTAINING A SULFAMATE BLEACH BOOSTER | The Procter and Gamble Company (US) | 2008-05-14 | — | — | EP | claimed |
| US-20070231283-A1 | Process for bleaching keratin fibers | PROCTER & GAMBLE COMPANY, THE | 2007-10-04 | — | — | US | claimed |
| US-20070067925-A1 | Agent for simultaneously lightening and coloring of fibers | PROCTER & GAMBLE COMPANY, THE | 2007-03-29 | — | — | US | claimed |
| WO-2007026327-A2 | PROCESS FOR BLEACHING KERATIN FIBERS | THE PROCTER & GAMBLE COMPANY (US) | 2007-03-08 | — | — | WO | claimed |
| WO-2007026328-A2 | AGENT FOR SIMULTANEOUS LIGHTENING AND COLORING OF KERATIN FIBRES CONTAINING A SULFAMATE BLEACH BOOSTER | THE PROCTER & GAMBLE COMPANY (US) | 2007-03-08 | — | — | WO | claimed |
| EP-1759684-A1 | Process for bleaching keratin fibers | Wella Aktiengesellschaft (DE) | 2007-03-07 | — | — | EP | claimed |
| EP-1759685-A1 | Agent for simultaneous lightening and coloring of keratin fibres containing a sulfamate bleach booster | Wella Aktiengesellschaft (DE) | 2007-03-07 | — | — | EP | claimed |
| EP-1919440-A2 | AGENT FOR SIMULTANEOUS LIGHTENING AND COLORING OF KERATIN FIBRES CONTAINING A SULFAMATE BLEACH BOOSTER | The Procter and Gamble Company (US) | 2008-05-14 | — | — | EP | disclosed |
| EP-1919439-A2 | PROCESS FOR BLEACHING KERATIN FIBERS | The Procter and Gamble Company (US) | 2008-05-14 | — | — | EP | disclosed |
| US-20070231283-A1 | Process for bleaching keratin fibers | PROCTER & GAMBLE COMPANY, THE | 2007-10-04 | — | — | US | disclosed |
| US-20070067925-A1 | Agent for simultaneously lightening and coloring of fibers | PROCTER & GAMBLE COMPANY, THE | 2007-03-29 | — | — | US | disclosed |
| WO-2007026327-A2 | PROCESS FOR BLEACHING KERATIN FIBERS | THE PROCTER & GAMBLE COMPANY (US) | 2007-03-08 | — | — | WO | disclosed |
| WO-2007026328-A2 | AGENT FOR SIMULTANEOUS LIGHTENING AND COLORING OF KERATIN FIBRES CONTAINING A SULFAMATE BLEACH BOOSTER | THE PROCTER & GAMBLE COMPANY (US) | 2007-03-08 | — | — | WO | disclosed |
| EP-1759685-A1 | Agent for simultaneous lightening and coloring of keratin fibres containing a sulfamate bleach booster | Wella Aktiengesellschaft (DE) | 2007-03-07 | — | — | EP | disclosed |
| EP-1759684-A1 | Process for bleaching keratin fibers | Wella Aktiengesellschaft (DE) | 2007-03-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070067925-A1 | Agent for simultaneously lightening and coloring of fibers | KIT, KRT18, H1-5 | CA2 132/4885CA1 434/4885KEAP1 307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.