Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 9/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.40 |
| ▸ | TNF | P01375 | 3/20 | 0.36 |
| ▸ | LITAF | Q99732 | 3/20 | 0.36 |
| ▸ | DPP4 | P27487 | 4/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.34 |
| ▸ | REN | P00797 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4598045 | 0.80 | SLC6A4 (0.43) | SLC6A2SLC6A4SLC6A3TNFLITAF | |
| SCHEMBL4597529 | 0.75 | BACE1 (0.38) | SLC6A2SLC6A4SLC6A3DPP4DRD2 | |
| SCHEMBL4596366 | 0.73 | CHRM2 (0.37) | SLC6A4SLC6A3DPP4DRD2DPP9 | |
| SCHEMBL4596721 | 0.73 | CHRM2 (0.37) | SLC6A4SLC6A3DPP4DRD2DPP9 | |
| SCHEMBL4429230 | 0.73 | MMP2 (0.35) | — | |
| SCHEMBL4597825 | 0.72 | CHRM2 (0.39) | SLC6A4DPP4DRD2DPP9HTR6 | |
| SCHEMBL4598352 | 0.71 | SLC6A4 (0.41) | SLC6A2SLC6A4SLC6A3TNFLITAF | |
| SCHEMBL4596506 | 0.71 | DRD2 (0.34) | SLC6A2SLC6A4SLC6A3TNFLITAF | |
| SCHEMBL4597256 | 0.71 | DRD2 (0.34) | SLC6A2SLC6A4SLC6A3TNFLITAF | |
| Hydrochloric Acid SCHEMBL8413869 | 0.70 | OPRM1 (0.35) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924265-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | Genzyme Corporation (US) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007022371-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORPORATION (US) | 2007-02-22 | — | — | WO | disclosed |