Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl 2-Hydroxy-5-Methoxybenzoate SCHEMBL643758 | 0.84 | CA1 (0.72) | HPGDALDH1A1CYP3A4MAPK1NPC1 | |
| SCHEMBL5267852 | 0.84 | CA12 (0.67) | HPGDALDH1A1CYP3A4MAPK1CA12 | |
| Methyl 2-Hydroxy-5-Methoxybenzoate SCHEMBL29709382 | 0.84 | CA1 (0.72) | HPGDALDH1A1CYP3A4MAPK1NPC1 | |
| SCHEMBL11615858 | 0.83 | ALDH1A1 (0.46) | HPGDALDH1A1CYP3A4MAPK1NPC1 | |
| SCHEMBL29445806 | 0.82 | ALDH1A1 (0.72) | HPGDALDH1A1CYP3A4MAPK1NPC1 | |
| SCHEMBL312754 | 0.82 | ALDH1A1 (0.72) | HPGDALDH1A1CYP3A4MAPK1NPC1 | |
| SCHEMBL28093168 | 0.80 | RAB9A (0.71) | HPGDALDH1A1CYP3A4MAPK1NPC1 | |
| SCHEMBL28548926 | 0.79 | HPGD (0.58) | HPGDALDH1A1CYP3A4MAPK1NPC1 | |
| SCHEMBL128781 | 0.78 | CA1 (0.61) | HPGDALDH1A1CYP3A4MAPK1NPC1 | |
| SCHEMBL29431885 | 0.78 | CA1 (0.61) | HPGDALDH1A1CYP3A4MAPK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1237872-B1 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECH INC (US) | 2008-02-27 | — | — | EP | disclosed |
| EP-1237872-A4 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECH INC (US) | 2005-06-15 | — | — | EP | disclosed |
| US-20050042274-A1 | Compounds and compositions for delivering active agents | MHR INSTITUTIONAL PARTNERS IIA LP | 2005-02-24 | — | — | US | disclosed |
| US-6693208-B2 | AMINO ACIDS WHICH DELIVER ACTIVE AGENTS TO SELECTED BIOLOGICAL SYSTEMS IN INCREASED OR IMPROVED BIOAVAILABILITY | EMISPHERE TECHNOLOGIES, INC. | 2004-02-17 | — | — | US | disclosed |
| US-20030216589-A1 | Compounds and compositions for delivering active agents | NOVO NORDISK NORTH AMERICA OPERATIONS A/S (DK) | 2003-11-20 | — | — | US | disclosed |
| EP-1237872-A1 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | Emisphere Technologies, Inc. (US) | 2002-09-11 | — | — | EP | disclosed |
| WO-2001044199-A1 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECHNOLOGIES, INC. (US) | 2001-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030216589-A1 | Compounds and compositions for delivering active agents | IDUA, ALG1, APOB | HPGD 2736/4885ALDH1A1 3939/4885CYP3A4 4837/4885 |
| US-20050042274-A1 | Compounds and compositions for delivering active agents | SERPINB1, ELANE, MMP8 | HPGD 861/4885ALDH1A1 2208/4885CYP3A4 3303/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.