SCHEMBL4624733

SCHEMBL4624733

COc1ccc(C(O)(c2ccccc2)c2ccc(O[Si](OC(C)(C)C)(c3ccccc3)c3ccccc3)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
AHR P35869 2/20 0.42
ACSS2 Q9NR19 2/20 0.39
KMT2A Q03164 1/20 0.38
CYP19A1 P11511 3/20 0.37
KIF11 P52732 6/20 0.37
KCNH2 Q12809 1/20 0.37
LMNA P02545 1/20 0.36
HTT P42858 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
AOC3 Q16853 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4624707 0.99 AHR (0.43) AHRACSS2KMT2ACYP19A1KIF11
SCHEMBL4626920 0.99 AHR (0.43) AHRACSS2KMT2ACYP19A1KIF11
SCHEMBL4625813 0.94 CYP19A1 (0.37) AHRACSS2KMT2ACYP19A1SMN1; SMN2
SCHEMBL4625906 0.94 CYP19A1 (0.37) AHRACSS2KMT2ACYP19A1SMN1; SMN2
SCHEMBL4625644 0.93 NR1H2 (0.35) AHRACSS2KMT2ACYP19A1SMN1; SMN2
SCHEMBL4627027 0.84 KIF11 (0.41) AHRKMT2AKIF11KCNH2LMNA
SCHEMBL29205 0.79 CA4 (0.54) AHRACSS2KMT2AKIF11KCNH2
SCHEMBL28797 0.79 CA4 (0.54) AHRACSS2KMT2AKIF11KCNH2
SCHEMBL4626091 0.75 ALDH1A1 (0.35) KMT2ALMNA
SCHEMBL4625876 0.74 ELANE (0.49)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1401851-B8 TWO-STAGE PROTECTIVE GROUPS FOR THE SYNTHESIS OF BIOPOLYMERS FEBIT HOLDING GMBH (DE) 2008-09-10 EP disclosed
EP-1401851-B1 TWO-STAGE PROTECTIVE GROUPS FOR THE SYNTHESIS OF BIOPOLYMERS FEBIT BIOTECH GMBH (DE) 2008-07-02 EP disclosed
US-7355036-B2 Two-stage protective groups for the synthesis of biopolymers FEBIT AG (DE) 2008-04-08 US disclosed
US-20040197851-A1 Two-stage protective groups for the synthesis of biopolymers MR. CHRISTOPHER SEAGON, ESQ. (DE) 2004-10-07 US disclosed
EP-1401851-A1 TWO-STAGE PROTECTIVE GROUPS FOR THE SYNTHESIS OF BIOPOLYMERS Febit AG (DE) 2004-03-31 EP disclosed
WO-2003004510-A1 TWO-STAGE PROTECTIVE GROUPS FOR THE SYNTHESIS OF BIOPOLYMERS FEBIT AG (DE) 2003-01-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040197851-A1 Two-stage protective groups for the synthesis of biopolymers CTRB2, OGG1, CPB2 AHR 1051/4885ACSS2 2355/4885KMT2A 2815/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.