Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16254251 | 0.71 | — | — | |
| SCHEMBL8207682 | 0.69 | — | — | |
| SCHEMBL26919084 | 0.69 | — | — | |
| SCHEMBL2100121 | 0.69 | — | — | |
| SCHEMBL148461 | 0.67 | — | — | |
| SCHEMBL331659 | 0.67 | — | — | |
| SCHEMBL4631599 | 0.67 | — | — | |
| SCHEMBL29206118 | 0.65 | — | — | |
| SCHEMBL5044835 | 0.65 | — | — | |
| SCHEMBL7519363 | 0.64 | EPHX1 (0.73) | EPHX1HTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1006136-A1 | Solid-liquid phase interfacial polymerisation | DOW CORNING CORPORATION (US) | 2000-06-07 | — | — | EP | claimed |
| US-6046293-A | Solid-liquid phase interfacial polymerization | UNIVERSITY OF SOUTH AUSTRALIA (AU) | 2000-04-04 | — | — | US | claimed |
| EP-0705864-B1 | Method of emulsion polymerization | DOW CORNING (US) | 2000-03-01 | — | — | EP | claimed |
| EP-0705864-A1 | Method of emulsion polymerization | DOW CORNING CORPORATION (US) | 1996-04-10 | — | — | EP | claimed |
| US-5504149-A | MIXING WATER, CYCLIC SILOXANE, NONIONIC SURFACTANT, CATIONIC SURFACTANT, ADDING SILANOLATE POLYMERIZATION INITIATOR, HEATING, AGITATING, POLYMERIZING TO SILICONE EMULSION | DOW CORNING CORPORATION (US) | 1996-04-02 | — | — | US | claimed |
| US-7449536-B2 | Branched polymers from organohydrogensilicon compounds | DOW CORNING CORPORATION (US) | 2008-11-11 | — | — | US | disclosed |
| EP-1572779-B1 | BRANCHED POLYMERS FROM ORGANOHYDROGENSILICON COMPOUNDS | DOW CORNING (US) | 2008-05-21 | — | — | EP | disclosed |
| US-20060074212-A1 | Branched polymers from organohydrogensilicon compounds | DOW CORNING CORPORATION (US) | 2006-04-06 | — | — | US | disclosed |
| EP-1572779-A2 | BRANCHED POLYMERS FROM ORGANOHYDROGENSILICON COMPOUNDS | Dow Corning Corporation (US) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004058857-A2 | BRANCHED POLYMERS FROM ORGANOHYDROGENSILICON COMPOUNDS | DOW CORNING CORPORATION (US) | 2004-07-15 | — | — | WO | disclosed |
| EP-0799852-B1 | Preparation of polyorganosiloxanes by interfacial polymerization | DOW CORNING (US) | 2003-09-24 | — | — | EP | disclosed |
| EP-1138715-A1 | Organosilicon compositions from cyclosiloxanes | DOW CORNING CORPORATION (US) | 2001-10-04 | — | — | EP | disclosed |
| EP-1006136-A1 | Solid-liquid phase interfacial polymerisation | DOW CORNING CORPORATION (US) | 2000-06-07 | — | — | EP | disclosed |
| US-6046293-A | Solid-liquid phase interfacial polymerization | UNIVERSITY OF SOUTH AUSTRALIA (AU) | 2000-04-04 | — | — | US | disclosed |
| EP-0705864-B1 | Method of emulsion polymerization | DOW CORNING (US) | 2000-03-01 | — | — | EP | disclosed |
| EP-0799851-A2 | Preparation of polyorganosilloxanes by interfacial polymerization | DOW CORNING CORPORATION (US) | 1997-10-08 | — | — | EP | disclosed |
| EP-0799852-A2 | Preparation of polyorganosiloxanes by interfacial polymerization | DOW CORNING CORPORATION (US) | 1997-10-08 | — | — | EP | disclosed |
| US-5637668-A | REACTING DIHALOSILOXANE COMPOUND AND ORGANOSILANOLATE AT INTERFACE OF TWO NONAQUEOUS SOLVENTS IMMISCIBLE IN EACH OTHER | DOW CORNING CORPORATION (US) | 1997-06-10 | — | — | US | disclosed |
| US-5629401-A | Preparation of polyorganosiloxanes by interfacial polymerization | DOW CORNING CORPORATION (US) | 1997-05-13 | — | — | US | disclosed |
| EP-0705864-A1 | Method of emulsion polymerization | DOW CORNING CORPORATION (US) | 1996-04-10 | — | — | EP | disclosed |