Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7642136 | 0.80 | MGAM (0.33) | MGAMGAASIMGAM2KMT2A | |
| SCHEMBL7641127 | 0.78 | KMT2A (0.34) | MGAMGAASIMGAM2KMT2A | |
| SCHEMBL3711207 | 0.72 | HSD17B1 (0.36) | MGAMGAASIMGAM2KMT2A | |
| SCHEMBL16253741 | 0.71 | ALDH1A1 (0.35) | MGAMGAASIMGAM2KMT2A | |
| SCHEMBL16250158 | 0.69 | POLB (0.33) | MGAMGAASIMGAM2KMT2A | |
| SCHEMBL6345936 | 0.69 | MAPT (0.41) | MGAMGAASIMGAM2KMT2A | |
| SCHEMBL8243047 | 0.69 | KMT2A (0.41) | MGAMGAASIMGAM2KMT2A | |
| SCHEMBL22787488 | 0.68 | HSD11B1 (0.53) | MGAMGAASIMGAM2KMT2A | |
| SCHEMBL3712186 | 0.68 | SIRT5 (0.42) | MGAMGAASIMGAM2KMT2A | |
| SCHEMBL1254599 | 0.68 | CYP2D6 (0.49) | MGAMGAASIMGAM2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1193243-B1 | NOVEL PROCESS FOR PRODUCING BICYCLIC AMINO ALCOHOL | SHIONOGI & CO (JP) | 2008-08-13 | — | — | EP | disclosed |
| EP-1808427-A2 | Novel processes for the preparation of bicyclic aminoalcohols | SHIONOGI & CO., LTD. (JP) | 2007-07-18 | — | — | EP | disclosed |
| US-7214832-B2 | Processes for the preparation of bicyclic aminoalcohols | SHIONOGI & CO., LTD. (JP) | 2007-05-08 | — | — | US | disclosed |
| US-20040171882-A1 | Novel processes for the preparation of bicyclic aminoalcohols | HONMA TSUNETOSHI (JP) | 2004-09-02 | — | — | US | disclosed |
| US-6723857-B1 | NORPINONE TO ITS BENZOTHIOPHENE CARBOXAMIDE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 2004-04-20 | — | — | US | disclosed |
| US-6465662-B1 | OXIDIZING 2-HYDROXYETHYL-10 NORPINAN-3-YL)-2-AMINE AMIDES OF OXY-SUBSTITUTED BENZOTHIOPHENECARBOXYLIC ACIDS TO FORM ALDEHYDES IN THE PRESENCE OF 2,2,6,6-TETRAMETHYLPIPERIDINE-1-OXYLS. | SHIONOGI & CO., LTD. (JP) | 2002-10-15 | — | — | US | disclosed |
| EP-1193243-A1 | NOVEL PROCESS FOR PRODUCING BICYCLIC AMINO ALCOHOL | SHIONOGI & CO., LTD. (JP) | 2002-04-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040171882-A1 | Novel processes for the preparation of bicyclic aminoalcohols | DOHH, OXER1, XDH | MGAM 4094/4885GAA 4455/4885SI 4767/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.