SCHEMBL465905

SCHEMBL465905

O=c1cc(Cl)sn1-c1ccc(OC(F)(F)F)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KAT2B Q92831 2/20 0.54
L3MBTL1 Q9Y468 2/20 0.40
POLB P06746 1/20 0.40
MAPT P10636 2/20 0.40
MAPK1 P28482 1/20 0.40
RECQL P46063 1/20 0.40
NPBWR1 P48145 2/20 0.38
MCHR1 Q99705 2/20 0.38
MPI P34949 1/20 0.38
PHOSPHO1 Q8TCT1 1/20 0.38
CHRM5 P08912 1/20 0.37
MEN1 O00255 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
KMT2A Q03164 1/20 0.37
KCNA5 P22460 1/20 0.37
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL465941 0.76 MEN1 (0.43) KAT2BL3MBTL1POLBMAPTNPBWR1
SCHEMBL465814 0.73 KAT2B (0.53) KAT2BL3MBTL1POLBMAPTMEN1
SCHEMBL2108805 0.70 KAT2B (0.73) KAT2BMAPTPHOSPHO1MEN1KMT2A
SCHEMBL28744537 0.70 L3MBTL1 (0.47) L3MBTL1POLBMAPTMAPK1RECQL
SCHEMBL15637842 0.67 NPBWR1 (0.46) L3MBTL1POLBMAPTMAPK1RECQL
SCHEMBL254957 0.65 MAPT (0.56) L3MBTL1MAPTMEN1KMT2APIM1
SCHEMBL3006629 0.65 MGLL (0.58) L3MBTL1POLBMAPTMAPK1MEN1
SCHEMBL10079859 0.65 NPBWR1 (0.42) L3MBTL1POLBMAPTMAPK1RECQL
SCHEMBL10059454 0.65 MAPT (0.50) L3MBTL1POLBMAPTMCHR1MEN1
SCHEMBL8592552 0.65 MAPT (0.46) L3MBTL1POLBMAPTMEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2343975-B1 SPINOSYN ANTIFOULING COMPOSITIONS, METHODS OF USE THEREOF AND ARTICLES PROTECTED FROM ATTACHMENT OF BIOFOULING ORGANISMS ENTARCO SA (GR) 2012-09-12 EP claimed
US-7934888-B2 Marine anti-foulant system and methods for using same VIV SUPPRESSION, INC. (US) 2011-05-03 US claimed
US-20090185867-A1 MARINE ANTI-FOULANT SYSTEM AND METHODS FOR USING SAME ASSET INTEGRITY MANAGEMENT SOLUTIONS, L.L.C., D/B/A AIMS INTERNATIONAL 2009-07-23 US claimed
US-6610282-B1 Biologically active compounds that slowly release the biologically active compound. These compositions may be directly incorporated into the locus to be protected or may be applied to a structure in a coating. ROHM AND HAAS COMPANY 2003-08-26 US claimed
US-20130228096-A1 SPINOSYN ANTIFOULING COMPOSITIONS, METHODS OF USE THEREOF AND ARTICLES PROTECTED FROM ATTACHMENT OF BIOFOULING ORGANISMS ENTARCO SA (GR) 2013-09-05 US disclosed
US-20130195790-A1 SPINOSYN ANTIFOULING COMPOSITIONS, METHODS OF USE THEREOF AND ARTICLES PROTECTED FROM ATTACHMENT OF BIOFOULING ORGANISMS ENTARCO SA (GR) 2013-08-01 US disclosed
US-8470381-B2 Spinosyn antifouling compositions, methods of use thereof and articles protected from attachment of biofouling organisms Kritikou, Christine (GR) 2013-06-25 US disclosed
EP-2343975-B1 SPINOSYN ANTIFOULING COMPOSITIONS, METHODS OF USE THEREOF AND ARTICLES PROTECTED FROM ATTACHMENT OF BIOFOULING ORGANISMS ENTARCO SA (GR) 2012-09-12 EP disclosed
EP-2343975-A2 SPINOSYN ANTIFOULING COMPOSITIONS, METHODS OF USE THEREOF AND ARTICLES PROTECTED FROM ATTACHMENT OF BIOFOULING ORGANISMS Entarco SA (GR) 2011-07-20 EP disclosed
US-20110172173-A1 SPINOSYN ANTIFOULING COMPOSITIONS, METHODS OF USE THEREOF AND ARTICLES PROTECTED FROM ATTACHMENT OF BIOFOULING ORGANISMS CHRISTINE KRITIKOU (ONE-THIRD INTEREST) (GR) 2011-07-14 US disclosed
US-7934888-B2 Marine anti-foulant system and methods for using same VIV SUPPRESSION, INC. (US) 2011-05-03 US disclosed
US-7807735-B2 mixing lignocellulosic material with a phenolic resin binder, adding to the mixture an emulsion of nonsaponified and saponified wax, an alkyl phenol component containing C20-C42 alkyl group; a polynaphthalenesulfonic salt as dispersant/surfactant and water; solidification; dimensionally stable HEXION SPECIALTY CHEMICALS, INC. (US) 2010-10-05 US disclosed
EP-0835604-A1 Halopropargyl compounds as marine antifouling agents ROHM AND HAAS COMPANY (US) 1998-04-15 EP disclosed
EP-0835605-A1 Phenylamides as marine antifouling agents ROHM AND HAAS COMPANY (US) 1998-04-15 EP disclosed
EP-0659847-B1 Anti-fouling compositions and fouling control of harmful aquatic organisms CHUGOKU MARINE PAINTS (JP) 1998-03-18 EP disclosed
US-5683686-A Anti-fouling compositions comprising N-phenylisothiazalone derivatives and fouling control of harmful aquatic organisms using same CHUGOKU MARINE PAINTS, LTD. (JP) 1997-11-04 US disclosed
US-5663436-A Isothiazolone derivative and microbicidal composition comprising the same as active ingredient SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-09-02 US disclosed
US-5552423-A BACTERICIDE, FUNGICIDE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-09-03 US disclosed
EP-0659847-A1 Anti-fouling compositions and fouling control of harmful aquatic organisms Chugoku Marine Paints, Ltd. (JP) 1995-06-28 EP disclosed
EP-0648757-A1 Isothiazolone derivative and microbicidal composition comprising the same as active ingredient SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-04-19 EP disclosed