SCHEMBL465941

SCHEMBL465941

O=c1c(Cl)c(Cl)sn1-c1ccc(OC(F)(F)F)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.43
MAPT P10636 2/20 0.43
KMT2A Q03164 2/20 0.43
RAB9A P51151 2/20 0.43
ALDH1A1 P00352 1/20 0.43
MC4R P32245 1/20 0.43
OPRK1 P41145 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
GPR35 Q9HC97 1/20 0.43
NPBWR1 P48145 2/20 0.41
MCHR1 Q99705 2/20 0.41
MPI P34949 4/20 0.40
PHOSPHO1 Q8TCT1 4/20 0.40
POLB P06746 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
KAT2B Q92831 1/20 0.40
MIF P14174 5/20 0.39
CYP1A2 P05177 1/20 0.37
CYP2D6 P10635 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL465905 0.76 KAT2B (0.54) MEN1MAPTKMT2ANPBWR1MCHR1
SCHEMBL465814 0.70 KAT2B (0.53) MEN1MAPTKMT2AALDH1A1POLB
SCHEMBL4319779 0.68 NPBWR1 (0.47) MAPTRAB9AALDH1A1GPR35NPBWR1
SCHEMBL254957 0.65 MAPT (0.56) MEN1MAPTKMT2AALDH1A1SMN1; SMN2
SCHEMBL3006629 0.65 MGLL (0.58) MEN1MAPTKMT2AALDH1A1NPSR1
SCHEMBL10079859 0.65 NPBWR1 (0.42) MEN1MAPTKMT2ARAB9ANPBWR1
SCHEMBL255564 0.64 CCR6 (0.50) MEN1MAPTKMT2AALDH1A1CYP1A2
SCHEMBL10059884 0.64 NPBWR1 (0.49) MAPTALDH1A1SMN1; SMN2NPBWR1MCHR1
SCHEMBL24997232 0.64 POLB (0.59) MEN1MAPTKMT2AALDH1A1SMN1; SMN2
SCHEMBL22864545 0.64 POLB (0.62) MEN1MAPTKMT2APOLBL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2343975-B1 SPINOSYN ANTIFOULING COMPOSITIONS, METHODS OF USE THEREOF AND ARTICLES PROTECTED FROM ATTACHMENT OF BIOFOULING ORGANISMS ENTARCO SA (GR) 2012-09-12 EP claimed
US-7934888-B2 Marine anti-foulant system and methods for using same VIV SUPPRESSION, INC. (US) 2011-05-03 US claimed
US-20090185867-A1 MARINE ANTI-FOULANT SYSTEM AND METHODS FOR USING SAME ASSET INTEGRITY MANAGEMENT SOLUTIONS, L.L.C., D/B/A AIMS INTERNATIONAL 2009-07-23 US claimed
US-6610282-B1 Biologically active compounds that slowly release the biologically active compound. These compositions may be directly incorporated into the locus to be protected or may be applied to a structure in a coating. ROHM AND HAAS COMPANY 2003-08-26 US claimed
US-20130228096-A1 SPINOSYN ANTIFOULING COMPOSITIONS, METHODS OF USE THEREOF AND ARTICLES PROTECTED FROM ATTACHMENT OF BIOFOULING ORGANISMS ENTARCO SA (GR) 2013-09-05 US disclosed
US-20130195790-A1 SPINOSYN ANTIFOULING COMPOSITIONS, METHODS OF USE THEREOF AND ARTICLES PROTECTED FROM ATTACHMENT OF BIOFOULING ORGANISMS ENTARCO SA (GR) 2013-08-01 US disclosed
US-8470381-B2 Spinosyn antifouling compositions, methods of use thereof and articles protected from attachment of biofouling organisms Kritikou, Christine (GR) 2013-06-25 US disclosed
EP-2343975-B1 SPINOSYN ANTIFOULING COMPOSITIONS, METHODS OF USE THEREOF AND ARTICLES PROTECTED FROM ATTACHMENT OF BIOFOULING ORGANISMS ENTARCO SA (GR) 2012-09-12 EP disclosed
EP-2314585-B1 Condensed benzamide compounds as inhibitors of vanilloid receptor subtype 1 (VR1) activity JAPAN TOBACCO INC (JP) 2012-09-12 EP disclosed
EP-2343975-A2 SPINOSYN ANTIFOULING COMPOSITIONS, METHODS OF USE THEREOF AND ARTICLES PROTECTED FROM ATTACHMENT OF BIOFOULING ORGANISMS Entarco SA (GR) 2011-07-20 EP disclosed
US-20110172173-A1 SPINOSYN ANTIFOULING COMPOSITIONS, METHODS OF USE THEREOF AND ARTICLES PROTECTED FROM ATTACHMENT OF BIOFOULING ORGANISMS CHRISTINE KRITIKOU (ONE-THIRD INTEREST) (GR) 2011-07-14 US disclosed
US-7934888-B2 Marine anti-foulant system and methods for using same VIV SUPPRESSION, INC. (US) 2011-05-03 US disclosed
EP-0835604-A1 Halopropargyl compounds as marine antifouling agents ROHM AND HAAS COMPANY (US) 1998-04-15 EP disclosed
EP-0835605-A1 Phenylamides as marine antifouling agents ROHM AND HAAS COMPANY (US) 1998-04-15 EP disclosed
EP-0659847-B1 Anti-fouling compositions and fouling control of harmful aquatic organisms CHUGOKU MARINE PAINTS (JP) 1998-03-18 EP disclosed
US-5683686-A Anti-fouling compositions comprising N-phenylisothiazalone derivatives and fouling control of harmful aquatic organisms using same CHUGOKU MARINE PAINTS, LTD. (JP) 1997-11-04 US disclosed
US-5663436-A Isothiazolone derivative and microbicidal composition comprising the same as active ingredient SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-09-02 US disclosed
US-5552423-A BACTERICIDE, FUNGICIDE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-09-03 US disclosed
EP-0659847-A1 Anti-fouling compositions and fouling control of harmful aquatic organisms Chugoku Marine Paints, Ltd. (JP) 1995-06-28 EP disclosed
EP-0648757-A1 Isothiazolone derivative and microbicidal composition comprising the same as active ingredient SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-04-19 EP disclosed