Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4662611 | 1.00 | CYP1A2 (0.47) | CYP1A2PTGS2PPARANPC1ALDH1A1 | |
| SCHEMBL9465134 | 0.79 | PTGS2 (0.52) | CYP1A2PTGS2ALDH1A1LMNAMAPT | |
| SCHEMBL9465136 | 0.79 | PTGS2 (0.52) | CYP1A2PTGS2ALDH1A1LMNAMAPT | |
| SCHEMBL4661128 | 0.77 | HDAC3 (0.48) | CYP1A2PPARAALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL29260522 | 0.75 | PTGS2 (0.55) | CYP1A2PTGS2NPC1ALDH1A1LMNA | |
| SCHEMBL4659908 | 0.75 | HDAC8 (0.45) | ALDH1A1LMNAMAPTMAPK1MEN1 | |
| SCHEMBL4659891 | 0.74 | GAA (0.47) | CYP1A2MEN1KMT2A | |
| SCHEMBL4659918 | 0.73 | PPARA (0.38) | PPARAALDH1A1KMT2ANOS2 | |
| SCHEMBL4661260 | 0.73 | VNN1 (0.44) | NPC1ALDH1A1LMNAMAPTRAB9A | |
| SCHEMBL2378111 | 0.72 | HDAC1 (0.46) | CYP1A2PPARAALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1627866-B1 | CARBOXYLIC ACID COMPOUND AND MEDICINE CONTAINING THE SAME | KOWA CO (JP) | 2008-12-24 | — | — | EP | disclosed |
| US-7109242-B2 | Carboxylic compound and medicine comprising the same | KOWA COMPANY, LTD. (JP) | 2006-09-19 | — | — | US | disclosed |
| EP-1627866-A1 | CARBOXYLIC ACID COMPOUND AND MEDICINE CONTAINING THE SAME | Kowa Company Ltd. (JP) | 2006-02-22 | — | — | EP | disclosed |
| US-20050009909-A1 | Carboxylic compound and medicine comprising the same | KOWA COMPANY, LTD. (JP) | 2005-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050009909-A1 | Carboxylic compound and medicine comprising the same | CPT1A, GPR119, PNLIP | CYP1A2 1111/4885PTGS2 1722/4885PPARA 68/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.