Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TOP1 | P11387 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 7/20 | 0.38 |
| ▸ | ITGB7 | P26010 | 7/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL466422 | 0.81 | ITGA4 (0.42) | KMT2AMAPTITGA4ITGB7BRD4 | |
| SCHEMBL466423 | 0.76 | BRD4 (0.42) | MAPTPTGS1ITGA4ITGB7BRD4 | |
| SCHEMBL29412194 | 0.70 | KMT2A (0.59) | KMT2ASMN1; SMN2MAPTTOP1SLC6A3 | |
| SCHEMBL434556 | 0.70 | KMT2A (0.59) | KMT2ASMN1; SMN2MAPTTOP1SLC6A3 | |
| SCHEMBL9956957 | 0.66 | HIF1A (0.41) | KMT2ABRD4BRD9 | |
| SCHEMBL17602007 | 0.66 | SLC6A3 (0.40) | KMT2ASMN1; SMN2MAPTTOP1SLC6A3 | |
| SCHEMBL2510100 | 0.66 | MAPT (0.53) | KMT2ASMN1; SMN2MAPTTOP1SLC6A3 | |
| SCHEMBL3760693 | 0.64 | NPSR1 (0.58) | KMT2ASMN1; SMN2MAPTTOP1SLC6A3 | |
| SCHEMBL28565017 | 0.64 | ALDH1A1 (0.56) | KMT2ASMN1; SMN2MAPTSLC6A3 | |
| SCHEMBL31517375 | 0.64 | KMT2A (0.68) | KMT2ASMN1; SMN2MAPTTOP1SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9096533-B2 | Pyridazinone compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-08-04 | — | — | US | disclosed |
| US-9096534-B2 | Pyridazinone compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-08-04 | — | — | US | disclosed |
| US-20150126738-A1 | PYRIDAZINONE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2015-05-07 | — | — | US | disclosed |
| US-20150126739-A1 | PYRIDAZINONE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2015-05-07 | — | — | US | disclosed |
| US-8962625-B2 | Pyridazinone compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-02-24 | — | — | US | disclosed |
| US-8541414-B2 | Pyridazinone compound and use thereof as herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-09-24 | — | — | US | disclosed |
| US-20120196750-A1 | PYRIDAZINONE COMPOUND AND USE THEREOF | KIJI TOSHIYUKI (JP) | 2012-08-02 | — | — | US | disclosed |
| US-20120028988-A1 | USE OF PYRIDAZINONE COMPOUND FOR CONTROL OF HARMFUL ARTHROPOD PESTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-02-02 | — | — | US | disclosed |
| EP-2405745-A1 | HERBICIDAL COMPOSITION | Sumitomo Chemical Company, Limited (JP) | 2012-01-18 | — | — | EP | disclosed |
| US-20110319266-A1 | HERBICIDAL COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-12-29 | — | — | US | disclosed |
| US-20100248964-A1 | HERBICIDAL COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-09-30 | — | — | US | disclosed |
| WO-2010104216-A1 | HERBICIDAL COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-09-16 | — | — | WO | disclosed |
| US-20100210462-A1 | HERBICIDAL COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-08-19 | — | — | US | disclosed |
| EP-2187745-A2 | HERBICIDAL COMPOSITION | Sumitomo Chemical Company, Limited (JP) | 2010-05-26 | — | — | EP | disclosed |
| EP-2187744-A2 | HERBICIDAL COMPOSITION COMPRISING A PYRIDAZINONE COMPOUND WITH A SPECIFIC HERBICIDE AND A SPECIFIC SAFENER | Sumitomo Chemical Company, Limited (JP) | 2010-05-26 | — | — | EP | disclosed |
| CN-101443317-A | Pyridazinone compound and herbicide containing the same | SUMITOMO CHEMICAL CO (JP) | 2009-05-27 | — | — | CN | disclosed |
| US-20090111696-A1 | Pyridazinone Compound and Use Thereof as herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-04-30 | — | — | US | disclosed |
| WO-2009035145-A2 | HERBICIDAL COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-03-19 | — | — | WO | disclosed |
| WO-2009035151-A2 | HERBICIDAL COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-03-19 | — | — | WO | disclosed |
| WO-2009035146-A2 | HERBICIDAL COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-03-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110319266-A1 | HERBICIDAL COMPOSITION | DDT, EGLN1, ELF3 | KMT2A 431/4885SMN1; SMN2 2025/4885MAPT 3582/4885 |
| US-20100248964-A1 | HERBICIDAL COMPOSITION | CHRM2, CHRM1, WEE1 | KMT2A 1221/4885SMN1; SMN2 4100/4885MAPT 4336/4885 |
| US-20150126738-A1 | PYRIDAZINONE COMPOUND AND USE THEREOF | PDXK, PLPBP, PNPO | KMT2A 1905/4885SMN1; SMN2 4687/4885MAPT 3369/4885 |
| US-20100210462-A1 | HERBICIDAL COMPOSITION | WEE1, WEE2, H1-3 | KMT2A 1478/4885SMN1; SMN2 3954/4885MAPT 4413/4885 |
| US-20120028988-A1 | USE OF PYRIDAZINONE COMPOUND FOR CONTROL OF HARMFUL ARTHROPOD PESTS | PLPBP, PNPO, PIR | KMT2A 2737/4885SMN1; SMN2 1710/4885MAPT 3453/4885 |
| US-20150126739-A1 | PYRIDAZINONE COMPOUND AND USE THEREOF | PDXK, PLPBP, PNPO | KMT2A 1905/4885SMN1; SMN2 4687/4885MAPT 3369/4885 |
| US-20120196750-A1 | PYRIDAZINONE COMPOUND AND USE THEREOF | PDXK, PLPBP, PNPO | KMT2A 1905/4885SMN1; SMN2 4687/4885MAPT 3369/4885 |
| US-20090111696-A1 | Pyridazinone Compound and Use Thereof as herbicides | PDXK, DDT, PLPBP | KMT2A 1333/4885SMN1; SMN2 4641/4885MAPT 3414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.