Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acrylamide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylamide SCHEMBL19665935 | 0.82 | TSHR (0.50) | ALDH1A1TSHRFGFR4 | |
| Acrylamide SCHEMBL400232 | 0.81 | TSHR (0.44) | ALDH1A1TSHRFGFR4 | |
| Acrylamide SCHEMBL23607548 | 0.80 | ALDH1A1 (0.52) | ALDH1A1TSHRFGFR4 | |
| SCHEMBL127765 | 0.79 | — | — | |
| Acrylamide SCHEMBL29153172 | 0.79 | ALDH1A1 (0.38) | ALDH1A1TSHRFGFR4 | |
| Acrylamide SCHEMBL29250079 | 0.78 | TSHR (0.50) | ALDH1A1TSHRFGFR4 | |
| Acrylamide SCHEMBL29249980 | 0.78 | TSHR (0.50) | ALDH1A1TSHRFGFR4 | |
| Acrylamide SCHEMBL2165108 | 0.76 | TSHR (0.39) | ALDH1A1TSHRFGFR4 | |
| Acrylic Acid SCHEMBL27808800 | 0.76 | ALDH1A1 (0.39) | ALDH1A1TSHRFGFR4 | |
| Acrylamide SCHEMBL23607541 | 0.76 | ALDH1A1 (0.52) | ALDH1A1TSHRFGFR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008152519-A2 | WATER-RESISTANT GYPSUM BOARDS | LAFARGE PLATRES (FR) | 2008-12-18 | — | — | WO | claimed |
| EP-1990325-A1 | Water-resistant gypsum boards | LAFARGE PLATRES (FR) | 2008-11-12 | — | — | EP | claimed |
| US-11690756-B2 | Polymers, thermochromic agents, and/or hydrogel compositions and apparatus, including products embodying the same, and methods and processes for making same | BIOFREEZE IP HOLDINGS, LLC (US) | 2023-07-04 | — | — | US | disclosed |
| EP-3606995-B1 | POLYMERS, THERMOCHROMIC AGENTS, AND/OR HYDROGEL COMPOSITIONS AND APPARATUS, INCLUDING PRODUCTS EMBODYING THE SAME, AND METHODS AND PROCESSES FOR MAKING SAME | SHANGHAI CHUANGSHI MEDICAL TECH GROUP CO LTD (CN) | 2023-06-07 | — | — | EP | disclosed |
| US-20210079559-A1 | MODIFIED CROSS-SECTION FIBER AND METHOD FOR MANUFACTURING SAME AND NONWOVEN FABRIC AND NOISE-ABSORBING AND -INSULATING MATERIAL COMPRISING MODIFIED CROSS-SECTION FIBER | MITSUBISHI CHEMICAL CORPORATION (JP) | 2021-03-18 | — | — | US | disclosed |
| US-20160273130-A1 | HIGH-SHRINKAGE ACRYLIC FIBER, SPUN YARN CONTAINING THE SAME, AND STEP PILE FABRIC USING THE SPUN YARN | MITSUBISHI RAYON CO., LTD. (JP) | 2016-09-22 | — | — | US | disclosed |
| WO-2008152519-A2 | WATER-RESISTANT GYPSUM BOARDS | LAFARGE PLATRES (FR) | 2008-12-18 | — | — | WO | disclosed |
| EP-1990325-A1 | Water-resistant gypsum boards | LAFARGE PLATRES (FR) | 2008-11-12 | — | — | EP | disclosed |
| US-6866931-B2 | Acrylic based composite fiber and method for production thereof, and fiber composite using the same | MITSUBISHI RAYON CO., LTD. (JP) | 2005-03-15 | — | — | US | disclosed |
| US-20040175565-A1 | Acrylic based composite fiber and method for production thereof, and fiber composite using the same | MITSUBISHI CHEMICAL CORPORATION (JP) | 2004-09-09 | — | — | US | disclosed |
| US-20040170835-A1 | Acrylic composite fiber and method for production thereof, and fiber composite using the same | MITSUBISHI RAYON CO., LTD. (JP) | 2004-09-02 | — | — | US | disclosed |
| EP-1424413-A1 | ACRYLIC COMPOSITE FIBER AND METHOD FOR PRODUCTION THEREOF, AND FIBER COMPOSITE USING THE SAME | Mitsubishi Rayon Co., Ltd. (JP) | 2004-06-02 | — | — | EP | disclosed |