Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | PARP14 | Q460N5 | 11/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.38 |
| ▸ | GABRE | P78334 | 1/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.38 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.38 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.38 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2532755 | 0.87 | KIF11 (0.46) | KIF11BCHEPARP14GABRPGABRD | |
| SCHEMBL5009823 | 0.81 | BCHE (0.46) | KIF11BCHEPARP14HTR2BHTR5A | |
| SCHEMBL7670606 | 0.79 | GABRP (0.47) | KIF11BCHEPARP14GABRPGABRD | |
| SCHEMBL668159 | 0.77 | ALDH1A1 (0.41) | ALDH1A1HSD17B10 | |
| SCHEMBL29733506 | 0.75 | KIF11 (0.63) | KIF11BCHEPARP14GABRPGABRD | |
| SCHEMBL208113 | 0.75 | KIF11 (0.63) | KIF11BCHEPARP14GABRPGABRD | |
| SCHEMBL668632 | 0.74 | ALDH1A1 (0.38) | BCHEALDH1A1HSD17B10 | |
| SCHEMBL20774242 | 0.74 | HPRT1 (0.50) | ALDH1A1HSD17B10 | |
| SCHEMBL29986487 | 0.74 | BCHE (0.64) | KIF11BCHEPARP14GABRPGABRD | |
| SCHEMBL147411 | 0.74 | BCHE (0.64) | KIF11BCHEPARP14GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113527317-B | Electroluminescent material and device | 北京夏禾科技有限公司 | 2023-12-26 | — | — | CN | claimed |
| US-6979414-B2 | laminated interlayer a carbazole derivative; organoluminesce element for automobile use; heat resistant; emits fluorescence even at high temperature | IDEMITSU KOSAN CO., LTD. (JP) | 2005-12-27 | — | — | US | claimed |
| US-20050222429-A1 | laminated interlayer a carbazole derivative; organoluminesce element for automobile use; heat resistant; emits fluorescence even at high temperature | IDEMITSU KOSAN CO., LTD. (JP) | 2005-10-06 | — | — | US | claimed |
| US-6660410-B2 | Organic luminescence layer having a carbazole derivative with a glass-transition temperature of 110 degrees C. or higher, and a phosphorescent dopant; possible triplet exciton state at room temperature | IDEMITSU KOSAN CO., LTD. (JP) | 2003-12-09 | — | — | US | claimed |
| US-20240067618-A1 | ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME | ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) | 2024-02-29 | — | — | US | disclosed |
| CN-113527317-B | Electroluminescent material and device | 北京夏禾科技有限公司 | 2023-12-26 | — | — | CN | disclosed |
| WO-2020085845-A1 | ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME | ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) | 2020-04-30 | — | — | WO | disclosed |
| US-20120165356-A1 | SPIROCYCLIC HETEROCYCLIC DERIVATIVES AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2012-06-28 | — | — | US | disclosed |
| EP-2399577-A1 | Use of N-containing spirocompounds for the enhancement of cognitive function | Adolor Corporation (US) | 2011-12-28 | — | — | EP | disclosed |
| US-8071611-B2 | Spirocyclic heterocyclic derivatives and methods of their use | ADOLOR CORPORATION (US) | 2011-12-06 | — | — | US | disclosed |
| US-8022060-B2 | Spirocyclic heterocyclic derivatives and methods of their use | ADOLOR CORPORATION (US) | 2011-09-20 | — | — | US | disclosed |
| US-20110218186-A1 | SPIROCYCLIC HETEROCYCLIC DERIVATIVES AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2011-09-08 | — | — | US | disclosed |
| WO-2008033299-A2 | USE OF N-CONTAINING SPIROCOMPOUNDS FOR THE ENHANCEMENT OF COGNITIVE FUNCTION | ADOLOR CORPORATION (US) | 2008-03-20 | — | — | WO | disclosed |
| US-7338962-B2 | Spirocyclic heterocyclic derivatives and methods of their use | ADOLOR CORPORATION (US) | 2008-03-04 | — | — | US | disclosed |
| EP-1871761-A2 | SPIROCYCLIC HETEROCYCLIC DERIVATIVES AND METHODS OF THEIR USE | Adolor Corporation (US) | 2008-01-02 | — | — | EP | disclosed |
| US-20060270695-A1 | Spirocyclic heterocyclic derivatives and methods of their use | CUBIST PHARMACEUTICALS, INC. | 2006-11-30 | — | — | US | disclosed |
| WO-2006105442-A2 | SPIROCYCLIC HETEROCYCLIC DERIVATIVES AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2006-10-05 | — | — | WO | disclosed |
| EP-1675847-A2 | SPIROCYCLIC HETEROCYCLIC DERIVATIVES AND METHODS OF THEIR USE | Adolor Corporation (US) | 2006-07-05 | — | — | EP | disclosed |
| US-20050159438-A1 | Spirocyclic heterocyclic derivatives and methods of their use | ADOLOR CORPORATION | 2005-07-21 | — | — | US | disclosed |
| WO-2005033073-A2 | SPIROCYCLIC HETEROCYCLIC DERIVATIVES AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2005-04-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110218186-A1 | SPIROCYCLIC HETEROCYCLIC DERIVATIVES AND METHODS OF THEIR USE | OPRK1, OPRD1, OPRL1 | KIF11 4543/4885BCHE 3809/4885PARP14 3968/4885 |
| US-20240067618-A1 | ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME | SOD1, L1CAM, ACHE | KIF11 3211/4885BCHE 628/4885PARP14 1036/4885 |
| US-20050222429-A1 | laminated interlayer a carbazole derivative; organoluminesce element for automobile use; heat resistant; emits fluorescence even at high temperature | IL33, HSF1, WEE1 | KIF11 1553/4885BCHE 3025/4885PARP14 3196/4885 |
| US-20060270695-A1 | Spirocyclic heterocyclic derivatives and methods of their use | OPRK1, OPRD1, OPRL1 | KIF11 4543/4885BCHE 3809/4885PARP14 3968/4885 |
| US-20120165356-A1 | SPIROCYCLIC HETEROCYCLIC DERIVATIVES AND METHODS OF THEIR USE | OPRK1, OPRD1, OPRL1 | KIF11 4543/4885BCHE 3809/4885PARP14 3968/4885 |
| US-20050159438-A1 | Spirocyclic heterocyclic derivatives and methods of their use | OPRK1, OPRD1, OPRL1 | KIF11 4543/4885BCHE 3809/4885PARP14 3968/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.