Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.51 |
| ▸ | DRD1 | P21728 | 4/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27635813 | 0.92 | PTGS2 (0.52) | PTGS2DRD1HTR7TDP1L3MBTL1 | |
| SCHEMBL10806869 | 0.91 | PTGS2 (0.50) | PTGS2DRD1 | |
| SCHEMBL27472703 | 0.87 | PTGS2 (0.51) | PTGS2DRD1NCOA1NCOA3ALDH1A1 | |
| SCHEMBL11416839 | 0.83 | PTGS2 (0.46) | PTGS2DRD1HTR7TDP1L3MBTL1 | |
| Iodide SCHEMBL8005565 | 0.83 | ABL1 (0.49) | PTGS2DRD1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL28257822 | 0.81 | ADRB2 (0.46) | PTGS2DRD1HTR7TDP1L3MBTL1 | |
| SCHEMBL3839152 | 0.80 | NFE2L2 (0.42) | PTGS2L3MBTL1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL19568051 | 0.80 | ELANE (0.55) | PTGS2DRD1HTR7TDP1L3MBTL1 | |
| SCHEMBL3478225 | 0.80 | TDP1 (0.46) | PTGS2HTR7TDP1L3MBTL1MAPK1 | |
| SCHEMBL9395043 | 0.80 | CA2 (0.55) | PTGS2DRD1HTR7TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2949655-B1 | REACTION CATALYST FOR CROSS COUPLING AND METHOD FOR MANUFACTURING AROMATIC COMPOUND | HOKKO CHEM IND CO (JP) | 2019-05-15 | — | — | EP | disclosed |
| EP-3170221-B1 | LIQUID FORMULATIONS, PROCESSES FOR THEIR MANUFACTURE, AND USE OF SUCH LIQUID FORMULATIONS | GOTION INC (US) | 2019-03-27 | — | — | EP | disclosed |
| CN-105008378-B | The manufacturing method of cross-coupling catalysts and aromatic compound | 北兴化学工业株式会社 | 2018-05-18 | — | — | CN | disclosed |
| US-20170214097-A1 | LIQUID FORMULATIONS, PROCESSES FOR THEIR MANUFACTURE, AND USE OF SUCH LIQUID FORMULATIONS | BASF SE (DE) | 2017-07-27 | — | — | US | disclosed |
| US-20170214097-A1 | LIQUID FORMULATIONS, PROCESSES FOR THEIR MANUFACTURE, AND USE OF SUCH LIQUID FORMULATIONS | BASF SE (DE) | 2017-07-27 | — | — | US | disclosed |
| US-9707551-B2 | Reaction catalyst for cross-coupling and method for manufacturing aromatic compound | HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) | 2017-07-18 | — | — | US | disclosed |
| WO-2016009052-A1 | LIQUID FORMULATIONS, PROCESSES FOR THEIR MANUFACTURE, AND USE OF SUCH LIQUID FORMULATIONS | BASF SE (DE) | 2016-01-21 | — | — | WO | disclosed |
| US-20150360214-A1 | REACTION CATALYST FOR CROSS-COUPLING AND METHOD FOR MANUFACTURING AROMATIC COMPOUND | HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) | 2015-12-17 | — | — | US | disclosed |
| EP-2949655-A1 | REACTION CATALYST FOR CROSS COUPLING AND METHOD FOR MANUFACTURING AROMATIC COMPOUND | Hokko Chemical Industry Co., Ltd. (JP) | 2015-12-02 | — | — | EP | disclosed |
| CN-105008378-A | Reaction catalyst for cross coupling and method for manufacturing aromatic compound | HOKKO CHEM IND CO | 2015-10-28 | — | — | CN | disclosed |
| WO-2005016886-A1 | SULFONYL SUBSTITUTED N-(BIARYLMETHYL) AMINOCYCLOPROPANECARBOXAMIDES | MERCK & CO., INC. (US) | 2005-02-24 | — | — | WO | disclosed |
| EP-1167372-B1 | 2,2-(Diaryl)vinylphosphine compound, palladium catalyst thereof, and process for producing arylamine, diaryl, or arylalkyne with the catalyst | TAKASAGO PERFUMERY CO LTD (JP) | 2003-12-10 | — | — | EP | disclosed |
| US-6455720-B1 | AS CATALYSTS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2002-09-24 | — | — | US | disclosed |
| US-20020058837-A1 | 2,2 (Diarlyl) Vinylphosphine compound, palladium catalyst thereof, and process for producing arylamine, diaryl, or arylalkyne with the catalyst | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2002-05-16 | — | — | US | disclosed |
| US-6365776-B1 | FROM ORGANOHALOGEN COMPOUND AND AMINE USING PALLADIUM COMPOUND CATALYST AND PROMOTER | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2002-04-02 | — | — | US | disclosed |
| US-20020035295-A1 | PROCESS FOR PRODUCING AROMATIC AMINES | TAKASAGO INTERNATIONAL CORPORATION | 2002-03-21 | — | — | US | disclosed |
| EP-1167372-A1 | 2,2-(Diaryl)vinylphosphine compound, palladium catalyst thereof, and process for producing arylamine, diaryl, or arylalkyne with the catalyst | Takasago International Corporation (JP) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000068237-A1 | PD- AND NI COMPLEXES OF BIPHENYL-2-YL-PHOSPHANES AND THEIR USE IN CATALYTIC C,C-, C,N- AND C,O-COUPLINGS | CLARIANT GMBH (DE) | 2000-11-16 | — | — | WO | disclosed |
| EP-0813560-A2 | SOLUBLE FLUORINATED POLY-P-PHENYLENES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-12-29 | — | — | EP | disclosed |
| WO-1996028491-A1 | SOLUBLE FLUORINATED POLY-P-PHENYLENES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-09-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020035295-A1 | PROCESS FOR PRODUCING AROMATIC AMINES | TYR, DDC, PNMT | PTGS2 3350/4885DRD1 281/4885HTR7 418/4885 |
| US-20020058837-A1 | 2,2 (Diarlyl) Vinylphosphine compound, palladium catalyst thereof, and process for producing arylamine, diaryl, or arylalkyne with the catalyst | DDT, PDCD11, PLD2 | PTGS2 2783/4885DRD1 99/4885HTR7 1208/4885 |
| US-20150360214-A1 | REACTION CATALYST FOR CROSS-COUPLING AND METHOD FOR MANUFACTURING AROMATIC COMPOUND | ALK, HRH4, HRH3 | PTGS2 2726/4885DRD1 442/4885HTR7 677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.