Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4694289 | 0.88 | HCRTR1 (0.51) | HCRTR1HCRTR2 | |
| SCHEMBL4691301 | 0.83 | HCRTR1 (0.44) | HCRTR1HCRTR2 | |
| SCHEMBL4689903 | 0.83 | P2RX7 (0.41) | — | |
| SCHEMBL4694455 | 0.82 | CHRNB2 (0.44) | — | |
| SCHEMBL4694336 | 0.81 | HCRTR1 (0.36) | HCRTR1HCRTR2 | |
| SCHEMBL4691673 | 0.80 | HCRTR1 (0.38) | HCRTR1HCRTR2 | |
| SCHEMBL4691928 | 0.80 | MAPK1 (0.41) | HCRTR1HCRTR2 | |
| SCHEMBL4692648 | 0.80 | HCRTR1 (0.42) | HCRTR1HCRTR2 | |
| SCHEMBL3284141 | 0.79 | CCR5 (0.42) | HCRTR1HCRTR2 | |
| SCHEMBL4691802 | 0.79 | CCR5 (0.48) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761542-B1 | OCTAHYDROPYRROLO[3,4-C]PYRROLE DERIVATIVES AN THEIR USE AS ANTIVIRAL AGENTS | HOFFMANN LA ROCHE (CH) | 2008-01-02 | — | — | EP | claimed |
| EP-1761542-B1 | OCTAHYDROPYRROLO[3,4-C]PYRROLE DERIVATIVES AN THEIR USE AS ANTIVIRAL AGENTS | HOFFMANN LA ROCHE (CH) | 2008-01-02 | — | — | EP | disclosed |