Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 13/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 13/20 | 0.42 |
| ▸ | CCR3 | P51677 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4694289 | 0.80 | HCRTR1 (0.51) | HCRTR1HCRTR2 | |
| SCHEMBL4694309 | 0.80 | HCRTR1 (0.39) | HCRTR1HCRTR2 | |
| SCHEMBL4694455 | 0.80 | CHRNB2 (0.44) | — | |
| SCHEMBL4689903 | 0.78 | P2RX7 (0.41) | — | |
| SCHEMBL4693659 | 0.78 | CHRNB2 (0.47) | — | |
| SCHEMBL4695117 | 0.78 | HDAC3 (0.41) | HCRTR1HCRTR2PDE2A | |
| SCHEMBL4692755 | 0.77 | ALDH1A1 (0.45) | — | |
| SCHEMBL4692415 | 0.77 | RAB9A (0.49) | — | |
| SCHEMBL4695295 | 0.77 | HSD17B10 (0.45) | HCRTR1HCRTR2PDE2A | |
| SCHEMBL4690222 | 0.77 | CHRNA4 (0.46) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761542-B1 | OCTAHYDROPYRROLO[3,4-C]PYRROLE DERIVATIVES AN THEIR USE AS ANTIVIRAL AGENTS | HOFFMANN LA ROCHE (CH) | 2008-01-02 | — | — | EP | claimed |
| EP-1761542-B1 | OCTAHYDROPYRROLO[3,4-C]PYRROLE DERIVATIVES AN THEIR USE AS ANTIVIRAL AGENTS | HOFFMANN LA ROCHE (CH) | 2008-01-02 | — | — | EP | disclosed |