Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.39 |
| ▸ | ITGAV | P06756 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | F2R | P25116 | 1/20 | 0.38 |
| ▸ | CCKBR | P32239 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7900498 | 0.89 | CCR1 (0.46) | ITGB3ITGA2BGAATAS1R3TAS1R1 | |
| SCHEMBL7904100 | 0.88 | ITGB3 (0.41) | ITGB3ITGA2BGAATAS1R3TAS1R1 | |
| SCHEMBL7892917 | 0.82 | ITGB3 (0.44) | ITGB3ITGA2BGAATAS1R3TAS1R1 | |
| SCHEMBL4701020 | 0.81 | P2RY12 (0.43) | ITGB3ITGA2BGAATAS1R3TAS1R1 | |
| SCHEMBL4698653 | 0.81 | LMNA (0.47) | ITGB3ITGA2BGAATAS1R3TAS1R1 | |
| SCHEMBL7900328 | 0.80 | ALDH1A1 (0.43) | ITGB3GAAITGAVALDH1A1LMNA | |
| SCHEMBL4702813 | 0.80 | ALDH1A1 (0.45) | ITGB3ITGA2BGAATAS1R3TAS1R1 | |
| SCHEMBL4698338 | 0.80 | ALDH1A1 (0.47) | GAATAS1R3TAS1R1ALDH1A1ADRA1D | |
| SCHEMBL4701238 | 0.78 | PKM (0.45) | ITGB3ITGA2BGAAALDH1A1F2R | |
| SCHEMBL7901896 | 0.78 | GAA (0.44) | ITGB3ITGA2BGAATAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6194448-B1 | ANTIINFLAMMATORY AGENTS; ASTHMA; RHEUMATIC DISORDERS | TEXAS BIOTECHNOLOGY CORPORATION | 2001-02-27 | — | — | US | disclosed |