SCHEMBL470910

SCHEMBL470910

FCCCOc1ccc2ccccc2c1

nearest known ligand 0.66

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.66
KDM4E B2RXH2 2/20 0.66
MAPK1 P28482 1/20 0.66
AGXT P21549 2/20 0.62
NPC1 O15118 3/20 0.56
RAB9A P51151 3/20 0.56
MAPT P10636 2/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
PPARG P37231 2/20 0.55
HTT P42858 1/20 0.54
ALOX5 P09917 1/20 0.53
HRH3 Q9Y5N1 5/20 0.53
DRD3 P35462 2/20 0.53
HDAC1 Q13547 1/20 0.51
PTPN7 P35236 1/20 0.50
ALDH1A1 P00352 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12668171 1.00 TDP1 (0.66) TDP1KDM4EMAPK1AGXTNPC1
SCHEMBL29550888 1.00 TDP1 (0.66) TDP1KDM4EMAPK1AGXTNPC1
SCHEMBL12354082 0.90 TDP1 (0.68) TDP1KDM4EMAPK1AGXTNPC1
SCHEMBL8565990 0.87 TDP1 (0.76) TDP1KDM4EMAPK1AGXTNPC1
SCHEMBL1859481 0.87 TDP1 (0.76) TDP1KDM4EMAPK1AGXTNPC1
SCHEMBL29429997 0.87 TDP1 (0.76) TDP1KDM4EMAPK1AGXTNPC1
SCHEMBL16902857 0.85 TDP1 (0.73) TDP1KDM4EMAPK1AGXTNPC1
SCHEMBL16902871 0.85 TDP1 (0.73) TDP1KDM4EMAPK1AGXTNPC1
SCHEMBL16902870 0.85 TDP1 (0.73) TDP1KDM4EMAPK1AGXTNPC1
SCHEMBL16902859 0.85 TDP1 (0.73) TDP1KDM4EMAPK1AGXTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022038631-A1 QUATERNARY AMMONIUM FLUORIDE SALTS FOR FLUORINATION REACTIONS COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2022-02-24 WO disclosed
US-20200407360-A1 Process for Producing Fluorinated Compounds Using Alcohol Solvent Having Unsaturated Hydrocarbon FUTURECHEM CO., LTD (KR) 2020-12-31 US disclosed
EP-1824805-B1 METHOD FOR PREPARATION OF ORGANOFLUORO COMPOUNDS IN ALCOHOL SOLVENTS FUTURECHEM CO LTD (KR) 2020-02-12 EP disclosed
EP-1824805-B1 METHOD FOR PREPARATION OF ORGANOFLUORO COMPOUNDS IN ALCOHOL SOLVENTS FUTURECHEM CO LTD (KR) 2020-02-12 EP disclosed
US-9751844-B2 Precursor compound connected to solid support for manufacturing 18F radiopharmaceutical, method for manufacturing same, and application thereof FUTURECHEM CO., LTD. (KR) 2017-09-05 US disclosed
US-20140011961-A1 PRECURSOR COMPOUND CONNECTED TO SOLID SUPPORT FOR MANUFACTURING 18F RADIOPHARMACEUTICAL, METHOD FOR MANUFACTURING SAME, AND APPLICATION THEREOF FUTURECHEM CO., LTD. (KR) 2014-01-09 US disclosed
WO-2012033374-A2 SULPHONATE PRECURSOR HAVING A 1,2,3-TRIAZOLIUM SALT, A PRODUCTION METHOD THEREFOR AND AN INTRAMOLECULAR NUCLEOPHILIC FLUORINATION REACTION USING THE SAME 서강대학교 산학협력단 (KR) 2012-03-15 WO disclosed
US-20110112293-A1 Purification Strategy for Direct Nucleophilic Procedures BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2011-05-12 US disclosed
US-7847092-B2 Method for preparation of F-18 containing organofluoro compounds in alcohol solvents FUTURECHEM CO., LTD. (KR) 2010-12-07 US disclosed
US-7847092-B2 Method for preparation of F-18 containing organofluoro compounds in alcohol solvents FUTURECHEM CO., LTD. (KR) 2010-12-07 US disclosed
US-20100113763-A1 METHOD FOR PREPARATION OF ORGANOFLUORO COMPOUNDS IN ALCOHOL SOLVENTS FUTURECHEM CO., LTD. (KR) 2010-05-06 US disclosed
US-20100113763-A1 METHOD FOR PREPARATION OF ORGANOFLUORO COMPOUNDS IN ALCOHOL SOLVENTS FUTURECHEM CO., LTD. (KR) 2010-05-06 US disclosed
US-20100113763-A1 METHOD FOR PREPARATION OF ORGANOFLUORO COMPOUNDS IN ALCOHOL SOLVENTS FUTURECHEM CO., LTD. (KR) 2010-05-06 US disclosed
WO-2009127372-A1 PURIFICATION STRATEGY FOR DIRECT NUCLEOPHILIC PROCEDURES BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2009-10-22 WO disclosed
US-20080171863-A1 Method for Preparing of Organofluoro Compounds in Alcohol Solvents FUTURECHEM CO., LTD. (KR) 2008-07-17 US disclosed
US-20080171863-A1 Method for Preparing of Organofluoro Compounds in Alcohol Solvents FUTURECHEM CO., LTD. (KR) 2008-07-17 US disclosed
US-20080171863-A1 Method for Preparing of Organofluoro Compounds in Alcohol Solvents FUTURECHEM CO., LTD. (KR) 2008-07-17 US disclosed
EP-1824805-A1 METHOD FOR PREPARATION OF ORGANOFLUORO COMPOUNDS IN ALCOHOL SOLVENTS Futurechem Co., Ltd. (KR) 2007-08-29 EP disclosed
WO-2006065038-A1 METHOD FOR PREPARATION OF ORGANOFLUORO COMPOUNDS IN ALCOHOL SOLVENTS FUTURECHEM CO., LTD. (KR) 2006-06-22 WO disclosed
WO-2003076366-A2 A METHOD FOR PREPARING ORGANIC FLUOROCOMPOUNDS CHEMTECH RESEARCH INCORPORATION (KR) 2003-09-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200407360-A1 Process for Producing Fluorinated Compounds Using Alcohol Solvent Having Unsaturated Hydrocarbon FASN, CYP2F1, FDFT1 TDP1 2600/4885KDM4E 3974/4885MAPK1 1383/4885
US-20080171863-A1 Method for Preparing of Organofluoro Compounds in Alcohol Solvents ADH5, ADH1C, ADH1A TDP1 2689/4885KDM4E 2630/4885MAPK1 2331/4885
US-20140011961-A1 PRECURSOR COMPOUND CONNECTED TO SOLID SUPPORT FOR MANUFACTURING 18F RADIOPHARMACEUTICAL, METHOD FOR MANUFACTURING SAME, AND APPLICATION THEREOF PFAS, RFT1, AFF1 TDP1 1603/4885KDM4E 2235/4885MAPK1 599/4885
US-20100113763-A1 METHOD FOR PREPARATION OF ORGANOFLUORO COMPOUNDS IN ALCOHOL SOLVENTS AFF1, AFF4, PFAS TDP1 2415/4885KDM4E 1931/4885MAPK1 1832/4885
US-20110112293-A1 Purification Strategy for Direct Nucleophilic Procedures MLX, SRM, STS TDP1 2209/4885KDM4E 269/4885MAPK1 4302/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.