Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.51 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | CTSB | P07858 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | TDO2 | P48775 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6512953 | 0.80 | PDE10A (0.60) | PDE10APOLBALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL29940575 | 0.80 | PDE10A (0.60) | PDE10APOLBALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL244559 | 0.78 | HSP90AA1 (0.59) | PDE10APOLBALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL294121 | 0.78 | PDE10A (0.58) | PDE10APOLBALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL13093318 | 0.78 | PDE10A (0.63) | PDE10APOLBALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL29579675 | 0.78 | PDE10A (0.58) | PDE10APOLBALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL57910 | 0.77 | PDE10A (0.56) | PDE10APOLBALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL1232447 | 0.77 | PAX8 (0.58) | PDE10APOLBALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL653567 | 0.77 | PDE10A (0.56) | PDE10APOLBALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL526500 | 0.77 | PDE10A (0.56) | PDE10APOLBALDH1A1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9580444-B2 | Polycyclic pyrazolinone derivative and herbicide comprising same as effective component thereof | SAGAMI CHEMICAL RESEARCH INSTITUTE (JP) | 2017-02-28 | — | — | US | disclosed |
| US-20160024110-A1 | POLYCYCLIC PYRAZOLINONE DERIVATIVE AND HERBICIDE COMPRISING SAME AS EFFECTIVE COMPONENT THEREOF | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2016-01-28 | — | — | US | disclosed |
| EP-2975040-A1 | POLYCYCLIC PYRAZOLINONE DERIVATIVE AND HERBICIDE COMPRISING SAME AS EFFECTIVE COMPONENT THEREOF | Sagami Chemical Research Institute (JP) | 2016-01-20 | — | — | EP | disclosed |
| US-9234225-B2 | Method for generating human milk oligosaccharides (HMOs) or precursors thereof | GLYCOM A/S (DK) | 2016-01-12 | — | — | US | disclosed |
| US-20150182549-A1 | METHOD FOR ENZYMATIC GLYCOSYLATION OF OLIGOSACCHARIDES FROM MAMMALIAN ANIMAL MILK | GLYCOM A/S (DK) | 2015-07-02 | — | — | US | disclosed |
| US-20150183816-A1 | MODIFIED GALACTOOLIGOSACCHARIDES | GLYCOM A/S (DK) | 2015-07-02 | — | — | US | disclosed |
| EP-2864492-A1 | MODIFIED GALACTOOLIGOSACCHARIDES | Glycom A/S (DK) | 2015-04-29 | — | — | EP | disclosed |
| EP-2864344-A1 | METHOD FOR ENZYMATIC GLYCOSYLATION OF OLIGOSACCHARIDES FROM MAMMALIAN ANIMAL MILK | Glycom A/S (DK) | 2015-04-29 | — | — | EP | disclosed |
| US-20140234912-A1 | METHOD FOR GENERATING HUMAN MILK OLIGOSACCHARIDES (HMOs) OR PRECURSORS THEREOF | GLYCOM A/S (DK) | 2014-08-21 | — | — | US | disclosed |
| EP-2707493-A1 | METHOD FOR GENERATING HUMAN MILK OLIGOSACCHARIDES (HMOs) OR PRECURSORS THEREOF | Glycom A/S (DK) | 2014-03-19 | — | — | EP | disclosed |
| WO-2013190531-A1 | GLYCOSYLATED GALACTOSYL DISACCHARIDES, METHODS FOR THEIR PRODUCTION AND THEIR USE IN CONSUMABLE PRODUCTS | GLYCOM A/S (DK) | 2013-12-27 | — | — | WO | disclosed |
| WO-2013190529-A1 | GLYCOSYLATED GALACTOSYL DISACCHARDDES, METHODS FOR THEIR PRODUCTION AND THEIR USE IN CONSUMABLE PRODUCTS | GLYCOM A/S (DK) | 2013-12-27 | — | — | WO | disclosed |
| WO-2013190530-A1 | MODIFIED GALACTOOLIGOSACCHARIDES | GLYCOM A/S (DK) | 2013-12-27 | — | — | WO | disclosed |
| WO-2012156897-A1 | METHOD FOR GENERATING HUMAN MILK OLIGOSACCHARIDES (HMOs) OR PRECURSORS THEREOF | GLYCOM A/S (DK) | 2012-11-22 | — | — | WO | disclosed |
| EP-1957073-A2 | MEDICINAL DRUG | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007066784-A2 | DIARYLETHER DERIVATIVES AS ANTITUMOR AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-06-14 | — | — | WO | disclosed |
| US-RE39590-E1 | Substituted benzene compounds, process for their preparation, and herbicidal and defoliant compositions containing them | ISK AMERICAS INCORPORATED (US) | 2007-04-24 | — | — | US | disclosed |
| CN-1680274-A | Substituted benzene compounds, process for their preparation, and herbicidal and defoliant compositions containing them | ISK AMERICAS INC (US) | 2005-10-12 | — | — | CN | disclosed |
| US-6545161-B2 | Potato and corn crops | ISK AMERICAS INCORPORATED | 2003-04-08 | — | — | US | disclosed |
| US-6355799-B1 | PREEMERGENT HERBICIDE FOR CEREAL CROP FIELDS, DEFOLIANT FOR POTATO AND COTTON PLANTS | ISK AMERICAS INCORPORATED | 2002-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160024110-A1 | POLYCYCLIC PYRAZOLINONE DERIVATIVE AND HERBICIDE COMPRISING SAME AS EFFECTIVE COMPONENT THEREOF | DDT, PDHX, CYP4X1 | PDE10A 1398/4885POLB 4658/4885ALDH1A1 596/4885 |
| US-20150182549-A1 | METHOD FOR ENZYMATIC GLYCOSYLATION OF OLIGOSACCHARIDES FROM MAMMALIAN ANIMAL MILK | GALE, SI, FUT6 | PDE10A 4136/4885POLB 1769/4885ALDH1A1 786/4885 |
| US-20150183816-A1 | MODIFIED GALACTOOLIGOSACCHARIDES | FUT6, GALE, FUT5 | PDE10A 3063/4885POLB 3227/4885ALDH1A1 1176/4885 |
| US-20140234912-A1 | METHOD FOR GENERATING HUMAN MILK OLIGOSACCHARIDES (HMOs) OR PRECURSORS THEREOF | LCT, B4GALT1, GALNT1 | PDE10A 4098/4885POLB 3097/4885ALDH1A1 2229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.