Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4729644 | 0.85 | CNR2 (0.46) | CNR2ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL8216865 | 0.80 | RAB9A (0.36) | ALDH1A1MEN1KMT2ARAB9AHTT | |
| SCHEMBL8207163 | 0.80 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AKDM4ERAB9A | |
| SCHEMBL8219508 | 0.77 | LMNA (0.40) | ALDH1A1MEN1KMT2ARAB9AHTT | |
| SCHEMBL8213285 | 0.76 | MAPT (0.45) | ALDH1A1KMT2AKDM4ERAB9AL3MBTL1 | |
| SCHEMBL8266779 | 0.76 | MAOB (0.44) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL8214695 | 0.75 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL8219294 | 0.72 | HPGDS (0.41) | KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL8213322 | 0.72 | PDGFRB (0.42) | ALDH1A1MEN1KMT2AKDM4EHTT | |
| SCHEMBL8217534 | 0.71 | LMNA (0.46) | ALDH1A1MEN1KMT2AKDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035049-A1 | ADAMANTANYL-(CYCLOPROPYL)-KETONES AS METABOTROPIC GLUTAMATE RECEPTOR MODULATORS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2008-03-27 | — | — | WO | disclosed |