Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 2/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | IGF1R | P08069 | 1/20 | 0.31 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4736394 | 0.88 | TGM2 (0.34) | TGM2BACE1KDRBRD4 | |
| SCHEMBL4732884 | 0.86 | EGFR (0.39) | TGM2PDGFRBEGFRERBB2CASP3 | |
| SCHEMBL4734122 | 0.78 | HTR1A (0.38) | — | |
| SCHEMBL4732880 | 0.76 | KMT2A (0.37) | PDGFRBEGFRERBB2IGF1RNOX4 | |
| SCHEMBL4734290 | 0.70 | HTR1A (0.35) | BRD4 | |
| SCHEMBL4734165 | 0.69 | TAAR1 (0.40) | — | |
| SCHEMBL4733337 | 0.69 | HTR1A (0.35) | BRD4 | |
| SCHEMBL4734123 | 0.69 | HTR1A (0.38) | — | |
| SCHEMBL4734722 | 0.68 | HCAR3 (0.33) | — | |
| SCHEMBL2814293 | 0.67 | PSEN1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008061029-A1 | ARYL SULFONAMIDE DERIVATIVES AND METHODS OF THEIR USE | WYETH (US) | 2008-05-22 | — | — | WO | disclosed |