SCHEMBL4734722

SCHEMBL4734722

CC(C)c1cc2c(cc1S(=O)(=O)Cl)S(=O)(=O)c1cc(F)ccc1C2(C)C

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HCAR3 P49019 1/20 0.33
HCAR2 Q8TDS4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4733059 0.84 TRPV4 (0.33)
SCHEMBL4734968 0.81 TRPV4 (0.36)
SCHEMBL4731674 0.78 PTGDR2 (0.33)
SCHEMBL4782344 0.78 HTR1A (0.37)
SCHEMBL4731516 0.76 MEN1 (0.39)
SCHEMBL4732731 0.76 CNR2 (0.38)
SCHEMBL4736394 0.75 TGM2 (0.34)
SCHEMBL4732090 0.75 AGBL2 (0.34) HCAR3HCAR2
SCHEMBL4734005 0.74 TBXAS1 (0.39)
SCHEMBL4730720 0.71 HCAR2 (0.33) HCAR3HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008061029-A1 ARYL SULFONAMIDE DERIVATIVES AND METHODS OF THEIR USE WYETH (US) 2008-05-22 WO disclosed