Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 3/20 | 0.42 |
| ▸ | PARP1 | P09874 | 3/20 | 0.42 |
| ▸ | PARP2 | Q9UGN5 | 3/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SCN1A | P35498 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CBX7 | O95931 | 3/20 | 0.33 |
| ▸ | CDYL2 | Q8N8U2 | 3/20 | 0.33 |
| ▸ | CDYL | Q9Y232 | 3/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1838649 | 0.87 | DRD2 (0.41) | USP2KMT2AALDH1A1CCR5DRD2 | |
| SCHEMBL4676164 | 0.86 | HSD11B1 (0.44) | TNKSPARP1PARP2HSD11B1SCN1A | |
| SCHEMBL3726211 | 0.79 | FPR2 (0.35) | TNKSPARP1PARP2USP2KMT2A | |
| SCHEMBL3724962 | 0.78 | HSD11B1 (0.38) | TNKSPARP1PARP2HSD11B1SCN1A | |
| SCHEMBL4739224 | 0.77 | KDM4E (0.48) | USP2SCN1ASCN5ASCN9AKMT2A | |
| SCHEMBL3806769 | 0.74 | FPR2 (0.41) | CCR5HRH3 | |
| SCHEMBL4734970 | 0.73 | LMNA (0.42) | KMT2ACCR5 | |
| SCHEMBL1838230 | 0.73 | TNKS (0.44) | TNKSPARP1PARP2HSD11B1ALDH1A1 | |
| SCHEMBL4674483 | 0.73 | ALDH1A1 (0.45) | TNKSPARP1PARP2USP2KMT2A | |
| SCHEMBL1841365 | 0.72 | PLD2 (0.45) | HSD11B1PLD1ALDH1A1CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1997805-A1 | Compounds with antiparasitic activity, applications thereof to the treatment of infectious diseases caused by apicomplexans | Commissariat à l'Energie Atomique (FR) | 2008-12-03 | — | — | EP | claimed |