Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I3 | Q14994 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
| ▸ | DHPS | P49366 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14104079 | 0.90 | CYP1A2 (0.36) | CYP1A2CYP3A4CYP2D6TSHRDHPS | |
| SCHEMBL11990372 | 0.89 | AR (0.39) | CYP1A2CYP3A4CYP2D6TSHRMEN1 | |
| SCHEMBL14104167 | 0.89 | KDM4E (0.35) | MEN1CYP2C19KMT2ALMNAALDH1A1 | |
| SCHEMBL4743431 | 0.89 | MAPK1 (0.40) | PDE4BPDE4DCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4740912 | 0.89 | ABCG2 (0.35) | CYP1A2CYP3A4CYP2D6TSHRDHPS | |
| SCHEMBL14103801 | 0.89 | PIK3CA (0.43) | CYP1A2CYP3A4CYP2D6TSHRMEN1 | |
| SCHEMBL14103886 | 0.88 | ABCG2 (0.44) | NR1I3CYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL4574851 | 0.86 | PRKCI (0.38) | CYP2C19MAPK1CYP2C9PRKCISCN9A | |
| SCHEMBL4740295 | 0.85 | PTGS1 (0.40) | MEN1CYP2C19KMT2AALDH1A1MAPK1 | |
| SCHEMBL4573992 | 0.84 | MAPK1 (0.44) | PDE4BPDE4DCYP2C19MAPK1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008092861-A1 | BICYCLIC DERIVATIVES AS EP4 AGONISTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-08-07 | — | — | WO | claimed |
| EP-2814526-B1 | COMPOSITIONS AND IMPROVED SOFT TISSUE REPLACEMENT METHODS | ALLERGAN INC (US) | 2016-11-02 | — | — | EP | disclosed |
| US-9334262-B2 | Methods of treating soft tissue defects | ALLERGAN, INC. (US) | 2016-05-10 | — | — | US | disclosed |
| US-9334262-B2 | Methods of treating soft tissue defects | ALLERGAN, INC. (US) | 2016-05-10 | — | — | US | disclosed |
| US-9005605-B2 | Compositions and soft tissue replacement methods | ALLERGAN, INC. (US) | 2015-04-14 | — | — | US | disclosed |
| US-9005605-B2 | Compositions and soft tissue replacement methods | ALLERGAN, INC. (US) | 2015-04-14 | — | — | US | disclosed |
| US-8926963-B2 | Compositions and soft tissue replacement methods | ALLERGAN, INC. (US) | 2015-01-06 | — | — | US | disclosed |
| US-8926963-B2 | Compositions and soft tissue replacement methods | ALLERGAN, INC. (US) | 2015-01-06 | — | — | US | disclosed |
| US-8900571-B2 | Compositions and soft tissue replacement methods | ALLERGAN, INC. (US) | 2014-12-02 | — | — | US | disclosed |
| US-8900571-B2 | Compositions and soft tissue replacement methods | ALLERGAN, INC. (US) | 2014-12-02 | — | — | US | disclosed |
| US-20120189589-A1 | COMPOSITIONS AND IMPROVED SOFT TISSUE REPLACEMENT METHODS | ALLERGAN, INC. (US) | 2012-07-26 | — | — | US | disclosed |
| US-20120189591-A1 | COMPOSITIONS AND IMPROVED SOFT TISSUE REPLACEMENT METHODS | ALLERGAN, INC. (US) | 2012-07-26 | — | — | US | disclosed |
| US-20120189591-A1 | COMPOSITIONS AND IMPROVED SOFT TISSUE REPLACEMENT METHODS | ALLERGAN, INC. (US) | 2012-07-26 | — | — | US | disclosed |
| US-20120189708-A1 | COMPOSITIONS AND IMPROVED SOFT TISSUE REPLACEMENT METHODS | ALLERGAN, INC. (US) | 2012-07-26 | — | — | US | disclosed |
| US-20120189708-A1 | COMPOSITIONS AND IMPROVED SOFT TISSUE REPLACEMENT METHODS | ALLERGAN, INC. (US) | 2012-07-26 | — | — | US | disclosed |
| US-20120142684-A1 | COMPOUNDS AND METHODS FOR SKIN REPAIR | ALLERGAN, INC. (US) | 2012-06-07 | — | — | US | disclosed |
| US-20120142684-A1 | COMPOUNDS AND METHODS FOR SKIN REPAIR | ALLERGAN, INC. (US) | 2012-06-07 | — | — | US | disclosed |
| US-20120136011-A1 | COMPOUNDS AND METHODS FOR SKIN REPAIR | ALLERGAN, INC. (US) | 2012-05-31 | — | — | US | disclosed |
| US-20120136011-A1 | COMPOUNDS AND METHODS FOR SKIN REPAIR | ALLERGAN, INC. (US) | 2012-05-31 | — | — | US | disclosed |
| WO-2008092861-A1 | BICYCLIC DERIVATIVES AS EP4 AGONISTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-08-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120189591-A1 | COMPOSITIONS AND IMPROVED SOFT TISSUE REPLACEMENT METHODS | MATR3, COL2A1, TNNC1 | NR1I3 3999/4885PDE4B 2326/4885PDE4D 1274/4885 |
| US-20120189708-A1 | COMPOSITIONS AND IMPROVED SOFT TISSUE REPLACEMENT METHODS | MATR3, COL2A1, TNNC1 | NR1I3 3999/4885PDE4B 2326/4885PDE4D 1274/4885 |
| US-20120189589-A1 | COMPOSITIONS AND IMPROVED SOFT TISSUE REPLACEMENT METHODS | MATR3, COL2A1, TNNC1 | NR1I3 3999/4885PDE4B 2326/4885PDE4D 1274/4885 |
| US-20120136011-A1 | COMPOUNDS AND METHODS FOR SKIN REPAIR | MMP8, COL14A1, COL1A1 | NR1I3 4511/4885PDE4B 631/4885PDE4D 711/4885 |
| US-20120142684-A1 | COMPOUNDS AND METHODS FOR SKIN REPAIR | MMP8, COL14A1, COL1A1 | NR1I3 4511/4885PDE4B 631/4885PDE4D 711/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.