Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4784046 | 0.88 | SMO (0.57) | SMONR3C1 | |
| SCHEMBL4735199 | 0.77 | NR3C1 (0.40) | SMONR3C1 | |
| SCHEMBL4737072 | 0.76 | SMO (0.42) | SMO | |
| SCHEMBL4736966 | 0.73 | NR3C1 (0.58) | NR3C1 | |
| SCHEMBL4784906 | 0.72 | NR3C1 (0.49) | SMONR3C1 | |
| SCHEMBL4738899 | 0.72 | DYRK1A (0.45) | — | |
| SCHEMBL27721784 | 0.70 | NR3C1 (0.56) | NR3C1 | |
| SCHEMBL4123094 | 0.70 | NR3C1 (0.56) | NR3C1 | |
| SCHEMBL995999 | 0.69 | LIPG (0.45) | — | |
| SCHEMBL21591549 | 0.69 | LMNA (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008079073-A1 | INDAZOLYL SULPHONAMIDE DERIVATIVES FOR THE TREATMENT OF GLUCOCORTICOID RECEPTOR MEDIATED DISORDERS | ASTRAZENECA AB (SE) | 2008-07-03 | — | — | WO | disclosed |