Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4786482 | 0.91 | TSHR (0.42) | KMT2AALDH1A1LMNARECQLTSHR | |
| SCHEMBL4788634 | 0.90 | SMN1; SMN2 (0.48) | KMT2AMAPTALDH1A1SMN1; SMN2HTT | |
| SCHEMBL4743021 | 0.88 | ALDH1A1 (0.42) | KMT2AMAPTALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL4787708 | 0.86 | SMN1; SMN2 (0.43) | ALDH1A1SMN1; SMN2HTTLMNARECQL | |
| SCHEMBL4746866 | 0.84 | HTT (0.48) | KMT2AMAPTALDH1A1SMN1; SMN2HTT | |
| SCHEMBL4788418 | 0.83 | THRB (0.47) | KMT2AMAPTALDH1A1SMN1; SMN2HTT | |
| SCHEMBL4743057 | 0.83 | ALDH1A1 (0.47) | KMT2AALDH1A1SMN1; SMN2HTTLMNA | |
| SCHEMBL4746102 | 0.82 | ACLY (0.44) | KMT2AMAPTALDH1A1SMN1; SMN2HTT | |
| SCHEMBL4787944 | 0.81 | SMN1; SMN2 (0.48) | KMT2AMAPTALDH1A1SMN1; SMN2HTT | |
| SCHEMBL4746166 | 0.81 | TSHR (0.43) | KMT2AMAPTALDH1A1SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008115259-A2 | DERIVATIVES OF BENZOXADIAZOLE SUITABLE FOR THE TREATMENT OF CELL PROLIFERATIVE DISEASES | RIGEL PHARMACEUTICALS, INC. (US) | 2008-09-25 | — | — | WO | claimed |